Results 31 to 40 of about 4,807 (202)
PLoS Neglected Tropical Diseases, 2022 BackgroundHemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses is a frequently reported acute hemorrhagic fever in South Korea. These viruses are transmitted by various rodent species such as Apodemus agrarius.Methodology/principal ...
Mi Hee Seo +5 more
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Processing of genome 5' termini as a strategy of negative-strand RNA viruses to avoid RIG-I-dependent interferon induction. [PDF]
PLoS ONE, 2008 Innate immunity is critically dependent on the rapid production of interferon in response to intruding viruses. The intracellular pathogen recognition receptors RIG-I and MDA5 are essential for interferon induction by viral RNAs containing 5 ...
Matthias Habjan +11 more
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Synthesis and Antiviral Activity of Camphene Derivatives against Different Types of Viruses
Molecules, 2021 To date, the ‘one bug-one drug’ approach to antiviral drug development cannot effectively respond to the constant threat posed by an increasing diversity of viruses causing outbreaks of viral infections that turn out to be pathogenic for humans ...
Anastasiya S. Sokolova +16 more
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Structural Characterization of the Full-length Hantaan Virus Polymerase
PLOS Pathogens, 2023 AbstractHantaviridaeare a family of segmented negative-sense RNA viruses that contains important human and animal pathogens including Andes orthohantavirus and Hantaan orthohantavirus.Hantaviridaecontain a viral RNA-dependent RNA polymerase that replicates and transcribes the viral genome in the cytoplasm of infected cells.
Keown JR +4 more
europepmc +5 more sources
Structural Studies of Hantaan Virus [PDF]
Journal of Virology, 2011 ABSTRACT Hantaan virus is the prototypic member of the Hantavirus genus within the family Bunyaviridae and is a causative agent of the potentially fatal hemorrhagic fever with renal syndrome.
Anthony J, Battisti +5 more
openaire +2 more sources
Pre-Clinical Studies of Inactivated Polyvalent HFRS Vaccine
Frontiers in Cellular and Infection Microbiology, 2020 Hemorrhagic fever with renal syndrome (HFRS) is the most common natural focal disease in the Russian Federation with about 6–12 thousand cases annually.
Tamara K. Dzagurova +10 more
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Hemorrhagic Fever with Renal Syndrome, Zibo City, China, 2006–2014
Emerging Infectious Diseases, 2016 Analysis of hemorrhagic fever with renal syndrome cases in Zibo City, China, during 2006–2014 showed that it occurred year-round. Peaks in spring and fall/winter were caused by Hantaan and Seoul viruses, respectively.
Ling Wang +7 more
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PLoS Pathogens, 2016 Segmented negative strand RNA viruses of the arena-, bunya- and orthomyxovirus families uniquely carry out viral mRNA transcription by the cap-snatching mechanism.
Juan Reguera +6 more
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HTNV infection of CD8+ T cells is associated with disease progression in HFRS patients
Communications Biology, 2021 Rongrong Liu et al. find that Hantaan virus, a common cause of hemorrhagic fever with renal syndrome (HFRS) in China, can infect CD8+ T cells and that these cells can support the full viral replication cycle.
Rongrong Liu +19 more
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Zoonotic Hantaviridae with Global Public Health Significance
Viruses, 2023 Hantaviridae currently encompasses seven genera and 53 species. Multiple hantaviruses such as Hantaan virus, Seoul virus, Dobrava-Belgrade virus, Puumala virus, Andes virus, and Sin Nombre virus are highly pathogenic to humans.
Rui-Xu Chen +8 more
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