Results 31 to 40 of about 1,691,113 (258)

Design and synthesis of HLA-A*02-restricted Hantaan virus multiple-antigenic peptide for CD8⁺ T cells. [PDF]

Virol J, 2020
Hantaan virus (HTNV) can cause hemorrhagic fever with renal syndrome (HFRS) in humans with severe morbidity and high mortality. Although inactivated HFRS vaccines are given annually for prevention in populations, China still has the highest number of ...
Ma Y, Tang K, Zhang Y, Zhang C, Zhang Y, Jin B, Ma Y.   +6 more
europepmc   +2 more sources

Protective CD8⁺ T-cell response against Hantaan virus infection induced by immunization with designed linear multi-epitope peptides in HLA-A2.1/K^b transgenic mice. [PDF]

Virol J, 2020
Background An effective vaccine that prevents disease caused by hantaviruses is a global public health priority, but up to now, no vaccine has been approved for worldwide use.
Ma Y, Tang K, Zhang Y, Zhang C, Cheng L, Zhang F, Zhuang R, Jin B, Zhang Y.   +8 more
europepmc   +2 more sources

Phylogenetic diversity and molecular evolution of Hantaan virus harbored by Apodemus chejuensis on Jeju Island, Republic of Korea, 2022-2023. [PDF]

PLoS Negl Trop Dis
Noh J, Park K, Kim SG, Seo YR, Kim J, Cho HK, Kim WK, Song JW.   +7 more
europepmc   +3 more sources

Phase 1 clinical trial of Hantaan and Puumala virus DNA vaccines delivered by needle-free injection [PDF]

npj Vaccines
Hantaan virus (HTNV) and Puumala virus (PUUV) are pathogenic zoonoses found in Asia and Europe, respectively. We conducted a randomized Phase 1 clinical trial of individual HTNV and PUUV DNA vaccines targeting the envelope glycoproteins (GnGc), as well ...
Jay W. Hooper, Steven A. Kwilas, Matthew Josleyn, Sarah L. Norris, Jack Hutter, Melinda Hamer, Jeffrey Livezey, Kristopher Paolino, Patrick Twomey, Michael Koren, Paul B. Keiser, James E. Moon, Ugo Nwaeze, Jason I. Koontz, Carmen Ledesma‐Feliciano, Nathalie Landry, Trevor Wellington   +16 more
openalex   +2 more sources

Incorporation of GM-CSF or CD40L Enhances the Immunogenicity of Hantaan Virus-Like Particles [PDF]

, 2016
A safe and effective Hantaan virus (HTNV) vaccine is highly desirable because HTNV causes an acute and often fatal disease (hemorrhagic fever with renal syndrome, HFRS).
Fang Wang, Fang-Lin Zhang, Lan Yu, Liang Zhang, Lin-Feng Cheng, Qi-Kang Ying, Wei Ye, Xing-An Wu, Zhi-Kai Xu, Zi-Yu Liu   +9 more
core   +4 more sources

Interferon-Induced Transmembrane Protein 3 Inhibits Hantaan Virus Infection, and Its Single Nucleotide Polymorphism rs12252 Influences the Severity of Hemorrhagic Fever with Renal Syndrome [PDF]

Frontiers in Immunology, 2017
Hantaan virus (HTNV) causes hemorrhagic fever with renal syndrome (HFRS). Previous studies have identified interferon-induced transmembrane proteins (IFITMs) as an interferon-stimulated gene family.
Bai Xue-fan, Bian Pei-yu, Huang Chang-xing, Jia Zhan-sheng, Lei Ying-feng, Ma Hong-wei, Tang Kang, Wang Ping-zhong, Wei Xin, Ye Chuan-tao, Ye Wei, Zhang Chun-mei, Zhang Ying, Zheng Xu-yang   +13 more
core   +2 more sources

Novel therapeutic approaches toward Hantaan virus and its clinical features' similarity with COVID-19.

Indian J Pharmacol, 2020
Zoonotic virus spill over in human community has been an intensive area of viral pathogenesis and the outbreak of Hantaan virus and severe acute respiratory syndrome coronavirus 2 (SARS CoV2) after late December 2019 caused a global threat. Hantaan virus
Singh H, Kaur H, Medhi B.
europepmc   +2 more sources

Hantaan virus infection induces human mucosal-associated invariant T cell pyroptosis through IRE1α pathway. [PDF]

Commun Biol
Zhang Y, Liu H, Liu D, Zhang H, Ma Y, Li N, Zhang C, Xue M, Wang F, Jia X, Zhang H, Tang K, Xu X, Wang S, Wei Y, Yang X, Zuo J, Chen L, Jin B, Zhang Y.   +19 more
europepmc   +2 more sources

T-cell immunoglobulin and mucin 1 (TIM-1) mediates infection of Hantaan virus in Jurkat T cells [PDF]

Virus Res
Ma R, Zheng X, Gu T, Liu Z, Hou S, Sun D, Ding Y, Wang F, Ying Q, Ma X, Kang H, Liu R, Lian J, Wu X.   +13 more
europepmc   +2 more sources

Seroepidemiology of Hantaan-related virus in Gabon [PDF]

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1987
Dupont, A., Georges, A., Gonzalez, Jean-Paul, Ivanoff, B.   +3 more
core   +4 more sources