Dynamic alterations of circulating lymphocytes during the trajectory of Hantaan virus-induced hemorrhagic fever with renal syndrome. [PDF]
Su L+11 more
europepmc +2 more sources
Hantaan virus infection induces human mucosal-associated invariant T cell pyroptosis through IRE1α pathway. [PDF]
Zhang Y+19 more
europepmc +2 more sources
A Brief History of Bunyaviral Family Hantaviridae
The discovery of Hantaan virus as an etiologic agent of hemorrhagic fever with renal syndrome in South Korea in 1978 led to identification of related pathogenic and nonpathogenic rodent-borne viruses in Asia and Europe.
Jens H. Kuhn, Connie S. Schmaljohn
doaj +1 more source
Chloroquine, an Anti-Malaria Drug as Effective Prevention for Hantavirus Infections
We investigated whether chloroquine can prevent hantavirus infection and disease in vitro and in vivo, using the Hantaan virus newborn C57BL/6 mice model and the Syrian hamster model for Andes virus.
Valentijn Vergote+5 more
doaj +1 more source
Structural Studies of Hantaan Virus [PDF]
ABSTRACT Hantaan virus is the prototypic member of the Hantavirus genus within the family Bunyaviridae and is a causative agent of the potentially fatal hemorrhagic fever with renal syndrome.
Colleen B. Jonsson+6 more
openaire +3 more sources
BackgroundHemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses is a frequently reported acute hemorrhagic fever in South Korea. These viruses are transmitted by various rodent species such as Apodemus agrarius.Methodology/principal ...
Mi Hee Seo+5 more
doaj +1 more source
Patch formation driven by stochastic effects of interaction between viruses and defective interfering particles [PDF]
Defective interfering particles (DIPs) are virus-like particles that occur naturally during virus infections. These particles are defective, lacking essential genetic materials for replication, but they can interact with the wild-type virus and potentially be used as therapeutic agents.
arxiv +1 more source
Nucleotide sequence of the L genome segment of Hantaan virus [PDF]
Connie S. Schmaljohn
openaire +4 more sources
Comparison of immunofluorescence and enzyme-linked immunosorbent assays for the serology of hantavirus infections. [PDF]
Three enzyme-linked immunosorbent assay (ELISA) systems based upon different principles were developed for the serology of Hantaan virus infections and compared with an indirect immunofluorescence assay (IFA).
Groen, G. (Guido) van der+3 more
core +5 more sources
Processing of genome 5' termini as a strategy of negative-strand RNA viruses to avoid RIG-I-dependent interferon induction. [PDF]
Innate immunity is critically dependent on the rapid production of interferon in response to intruding viruses. The intracellular pathogen recognition receptors RIG-I and MDA5 are essential for interferon induction by viral RNAs containing 5 ...
Matthias Habjan+11 more
doaj +1 more source