Results 61 to 70 of about 4,807 (202)

Unraveling the Mechanistic Links Between Species Diversity and Infection Risk From Zoonotic Pathogens With Direct Transmission Among Reservoir Hosts: Rodent‐Orthohantavirus Systems as Models

Ecology and Evolution, Volume 15, Issue 6, June 2025.
In this review, we synthesize mechanistic evidence for diversity‐disease patterns in rodent‐orthohantavirus systems in the Americas, models of directly transmitted disease systems. We found that host regulation has been examined the most while other mechanisms have received less attention. Based on our findings, we propose that for a negative diversity‐
Andreas Eleftheriou, Angela D. Luis
wiley   +1 more source

Real-time PCR assay development for the control of vaccine against hemorrhagic fever with renal syndrome

Вопросы вирусологии, 2021
Introduction. Hemorrhagic fever with renal syndrome (HFRS) holds a leading place among natural focal human diseases in Russian Federation. There is no etiotropic therapy for the disease now. The vaccine prophylaxis is the most effective method to control
M. S. Egorova, S. S. Kurashova, A. A. Ishmukhametov, M. V. Balovneva, A. A. Deviatkin, M. V. Safonova, S. V. Ozherelkov, Yu. Kh. Khapchaev, A. S. Balkina, A. V. Belyakova, T. K. Dzagurova, E A. Tkachenko   +11 more
doaj   +1 more source

Combating SARS-CoV-2: leveraging microbicidal experiences with other emerging/re-emerging viruses [PDF]

PeerJ, 2020
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan City, China, late in December 2019 is an example of an emerging zoonotic virus that threatens public health and international travel and commerce.
M. Khalid Ijaz, Syed A. Sattar, Joseph R. Rubino, Raymond W. Nims, Charles P. Gerba   +4 more
doaj   +2 more sources

Land Use Change and Infectious Disease Emergence

Reviews of Geophysics, Volume 63, Issue 2, June 2025.
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli, Paolo D’Odorico, Nikolas Galli, Reju S. John, Renata L. Muylaert, Monia Santini, David T. S. Hayman   +6 more
wiley   +1 more source

In-Cell Western Assays to Evaluate Hantaan Virus Replication as a Novel Approach to Screen Antiviral Molecules and Detect Neutralizing Antibody Titers

Frontiers in Cellular and Infection Microbiology, 2017
Hantaviruses encompass rodent-borne zoonotic pathogens that cause severe hemorrhagic fever disease with high mortality rates in humans. Detection of infectious virus titer lays a solid foundation for virology and immunology researches.
Hong-Wei Ma, Wei Ye, He-Song Chen, Tie-Jian Nie, Lin-Feng Cheng, Liang Zhang, Pei-Jun Han, Xing-An Wu, Zhi-Kai Xu, Ying-Feng Lei, Fang-Lin Zhang   +10 more
doaj   +1 more source

Innate Immunity Never “NODs” Off: NLRs Regulate the Host Anti‐Viral Immune Response

Immunological Reviews, Volume 330, Issue 1, March 2025.
ABSTRACT A robust innate immune response is essential in combating viral pathogens. However, it is equally critical to quell overzealous immune signaling to limit collateral damage and enable inflammation resolution. Pattern recognition receptors are critical regulators of these processes.
Mackenzie K. Woolls, Madeline D. Mott, Cassandra S. Poole, Julia A. Gregory, Hannah M. Ivester, Irving Coy Allen   +5 more
wiley   +1 more source

Pre-Clinical Studies of Inactivated Polivalent Vaccine Against Hemorrhagic Fever with Renal Syndrome

Эпидемиология и вакцинопрофилактика, 2019
Relevance. Hemorrhagic fever with renal syndrome (HFRS) is a non-transmissible viral zoonosis widespread in Eurasia, and in Russia it occupies a leading position among zoonotic viral infections and one of the first places among all natural focal human ...
A. A. Sinyugina, T. K. Dzagurova, A. A. Ishmukhametov, M. V. Balovneva, S. S. Kurashova, N. A. Korotina, M. S. Egorova, E. A. Tkachenko   +7 more
doaj   +1 more source

Evaluation and validation on cellular immunoreactivity of Hantaan virus Gc

陆军军医大学学报, 2023
Objective To screen, identify and verify the immunoreactive epitopes on Hantaan virus glycoprotein C-terminal (HTNV Gc). Methods On the basis of predicting the major histocompatibility complex (MHC) gene in more than 98% of the global population, the ...
XIE Mingyang, SUN Baozeng, MA Sijie, YANG Duan, LUO Cheng   +4 more
doaj   +1 more source

Wildlife Pathogens and Zoonotic Disease Risk Assessment in Vietnam: A Wildlife Trade Hotspot

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Vietnam is a wildlife trade hotspot presenting multiple high‐risk interfaces for pathogen spillover from wildlife to humans. However, the zoonotic disease risk remains poorly characterized in the country and needs to be assessed to better inform policy dialog and legislative reforms.
Alice Latinne, Pawin Padungtod, Fedor Korennoy   +2 more
wiley   +1 more source

Monoclonal antibodies specific for Hantaan virus.

Proceedings of the National Academy of Sciences, 1983
Six hybridoma cell line producing monoclonal antibodies to Hantaan virus were established by fusion of NS-1 mouse myeloma cells with spleen cells of mice immunized with Hantaan virus strain 76-118. The specificity of these monoclonal antibodies was established by immunoblotting analysis and immunofluorescence.
M C, Franko, C J, Gibbs, P W, Lee, D C, Gajdusek   +3 more
openaire   +3 more sources