Results 71 to 80 of about 4,807 (202)

Evaluation of a Luminex‐Based Multiplex Immunoassay of Hemorrhagic Fever Viruses in Senegal

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Given the growing threat posed by viral hemorrhagic fevers, the development of surveillance tools is crucial to provide accurate and rapid solutions. Public health response involves risk assessment as well as effective and sustainable surveillance to ensure downstream communication and preparedness. A serological approach that offers high precision and
Safietou Sankhe, Maryam Diarra, Mamadou Aliou Barry, Martin Faye, Cheikh Talla, Diogop Camara, Maimouna Mbanne, Pape Mbacke Sembene, Amadou Alpha Sall, Gamou Fall, Oumar Faye, Cheikh Loucoubar, Ousmane Faye, Ines Vigan-Womas, Keersten Michelle Ricks, Jessica Radzio-Basu, Moussa Moise Diagne, Leyi Wang   +17 more
wiley   +1 more source

Multiplex PCR-Based Nanopore Sequencing and Epidemiological Surveillance of Hantaan orthohantavirus in Apodemus agrarius, Republic of Korea

Viruses, 2021
Whole-genome sequencing of infectious agents enables the identification and characterization of emerging viruses. The MinION device is a portable sequencer that allows real-time sequencing in fields or hospitals.
Kyungmin Park, Seung-Ho Lee, Jongwoo Kim, Jingyeong Lee, Geum-Young Lee, Seungchan Cho, Seung Ho Lee, Kkothanahreum Park, Jin Sun No, Shailesh Budhathoki, Yu-Jin Kim, Young-Su Kim, Heung-Chul Kim, Terry A. Klein, Won-Keun Kim, Jin-Won Song   +15 more
doaj   +1 more source

Metatranscriptomic Analysis Uncovers RNA Virus Diversity in Ticks From the China–Russia–North Korea Border Region

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Ticks serve as critical viral vectors, and border regions, acting as convergence zones of complex ecosystems, provide diverse habitats for ticks and their hosts, thereby underscoring the need to investigate the tick‐borne virome composition in such areas. In this study, metatranscriptomic analysis of five tick species, namely Haemaphysalis longicornis,
Zhe Liu, Shengwei Ji, Jinqi Wang, Yuan Li, Eloiza May Galon, Shanshan Wang, Jixu Li, Xu Gao, Longzheng Yu, Yang Wang, Jianchen Song, Qichao Cui, Chenghui Li, Zhiqiang Xu, Shujiang Xue, Kamani Joshua   +15 more
wiley   +1 more source

A nomogram and heat map based on LASSO‐Cox regression for predicting the risk of early‐stage severe fever with thrombocytopenia syndrome patients developing into critical illness at 7‐day and 14‐day

Journal of Medical Virology, Volume 96, Issue 9, September 2024.
Abstract Severe fever with thrombocytopenia syndrome (SFTS) represents an emerging infectious disease characterized by a substantial mortality risk. Early identification of patients is crucial for effective risk assessment and timely interventions. In the present study, least absolute shrinkage and selection operator (LASSO)‐Cox regression analysis was
Hanwen Tong, Jun Wang, Naisheng Zhu, Haopeng Li, Yu Zhai, Binxia Shao, Huiying Li, Peng Xia, Yunfei Jiang, Chenxiao Jiang, Yun Liu   +10 more
wiley   +1 more source

Structural characterization of the oligomerization of full-length Hantaan virus polymerase into symmetric dimers and hexamers

Nature Communications
Hantaan virus is a dangerous human pathogen whose segmented negative-stranded RNA genome is replicated and transcribed by a virally-encoded multi-functional polymerase.
Quentin Durieux Trouilleton, Dominique Housset, Paco Tarillon, Benoît Arragain, Hélène Malet   +4 more
doaj   +1 more source

THE DYNAMICS OF ORTHOHANTAVIRUS HANTAAN STRAINS REPLICATION ON THE MODEL OF MOUSE PERITONEAL MACROPHAGES

Acta Biomedica Scientifica, 2018
Orthohantaviruses (Orthohantavirus genus, Hantaviridae family) are the causative agents of a widespread natural focal infection in the  Russian Federation, hemorrhagic fever with renal syndrome (HFRS).
A. B. Pott, O. V. Iunikhina, I. N. Lyapun, G. G. Kompanets   +3 more
doaj   +1 more source

Human behaviors driving disease emergence

Evolutionary Anthropology: Issues, News, and Reviews, Volume 33, Issue 2, April 2024.
Abstract Interactions between humans, animals, and the environment facilitate zoonotic spillover—the transmission of pathogens from animals to humans. Narratives that cast modern humans as exogenous and disruptive forces that encroach upon “natural” disease systems limit our understanding of human drivers of disease.
Sagan Friant
wiley   +1 more source

cGAS–STING‐mediated novel nonclassic antiviral activities

Journal of Medical Virology, Volume 96, Issue 2, February 2024.
Abstract Stimulatorof interferon genes (STING) is an intracellular sensor of cyclic dinucleotides involved in the innate immune response against pathogen‐ or self‐derived DNA. For years, interferon (IFN) induction of cyclic GMP–AMP synthase (cGAS)–STING has been considered as a canonical pattern defending the host from viral invasion.
Ying Hu, Runxin Ye, Jiaming Su, Yajuan Rui, Xiao‐Fang Yu   +4 more
wiley   +1 more source

Spatial risk of Haemaphysalis longicornis borne Dabieshan tick virus (DBTV) in China

Journal of Medical Virology, Volume 96, Issue 1, January 2024.
Abstract The uncertainty and unknowability of emerging infectious diseases have caused many major public health and security incidents in recent years. As a new tick‐borne disease, Dabieshan tick virus (DBTV) necessitate systematic epidemiological and spatial distribution analysis.
Xiaohu Han, Shan Gao, Qing Xin, Mingwei Yang, Yudan Bi, Feng Jiang, Zan Zeng, Wei Kan, Tongyao Wang, Qijun Chen, Zeliang Chen   +10 more
wiley   +1 more source

Investigating the Impact of HTNV Infection on the Gut Microbiota of Wild‐Type and NLRX1 Knockout Mice

Advanced Gut &Microbiome Research, Volume 2024, Issue 1, 2024.
It is becoming increasingly clear that maintaining the equilibrium of gut microbiota homeostasis during viral infections, such as Hantaan virus (HTNV), is of paramount importance. In order to gain insight into the role of NOD‐like receptors in the immune system, we conducted a comparative study between C57BL/6 and Nlrx1-/- mouse models to analyze ...
Wenjie Sun, Yaxin Ding, Ziyu Liu, Shiyuan Hou, Danni Sun, Ruixue Ma, Huarui Kang, Xiaohan Ma, Jiayu Wang, Hongrui Mu, Yunhua Lv, Tianle Gu, Qikang Ying, Fang Wang, Xingan Wu, Rongrong Liu, Faisal Rasheed   +16 more
wiley   +1 more source