Results 71 to 80 of about 8,666 (240)
Rodent-to-human transmission of hantaviruses is associated with severe disease. Currently, no FDA-approved, specific antivirals or vaccines are available, and the requirement for high biocontainment (biosafety level 3 [BSL-3]) laboratories limits ...
Megan M. Slough+2 more
doaj +1 more source
Improving the identification of antigenic sites in the H1N1 Influenza virus through accounting for the experimental structure in a sparse hierarchical Bayesian model [PDF]
Understanding how genetic changes allow emerging virus strains to escape the protection afforded by vaccination is vital for the maintenance of effective vaccines. In the current work, we use structural and phylogenetic differences between pairs of virus strains to identify important antigenic sites on the surface of the influenza A(H1N1) virus through
arxiv +1 more source
Combating SARS-CoV-2: leveraging microbicidal experiences with other emerging/re-emerging viruses [PDF]
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan City, China, late in December 2019 is an example of an emerging zoonotic virus that threatens public health and international travel and commerce.
M. Khalid Ijaz+4 more
doaj +2 more sources
Functional analysis of the Bunyamwera orthobunyavirus Gc glycoprotein [PDF]
The virion glycoproteins Gn and Gc of Bunyamwera orthobunyavirus (family Bunyaviridae) are encoded by the M RNA genome segment and have roles in both viral attachment and membrane fusion.
Brauburger, K.+4 more
core +2 more sources
SARS-CoV-2 Virus-Like Particles with Plasmonic Au Cores and S1-Spike Protein Coronas [PDF]
The COVID-19 pandemic has stimulated the scientific world to intensify virus-related studies, aimed at the development of quick and safe ways of detecting viruses in human body, studying the virus-antibody and virus-cell interactions, and designing nanocarriers for targeted antiviral therapies.
arxiv
Hemorrhagic fever with renal syndrome:pathogenesis and clinical picture
Hantaan virus (HTNV) causes hemorrhagic fever with renal syndrome (HFRS), which is a zoonosis endemic in eastern Asia, especially in China. The reservoir host of HTNV is field mouse (Apodemus agraricus).
Hong eJiang+4 more
doaj +1 more source
Introduction. Hemorrhagic fever with renal syndrome (HFRS) holds a leading place among natural focal human diseases in Russian Federation. There is no etiotropic therapy for the disease now. The vaccine prophylaxis is the most effective method to control
M. S. Egorova+11 more
doaj +1 more source
Hemorrhagic Fever with Renal Syndrome in 4 US Soldiers, South Korea, 2005
Four US soldiers acquired hemorrhagic fever with renal syndrome while training near the Demilitarized Zone, South Korea, in 2005. Hantaan virus sequences were amplified by reverse transcription–PCR from patient serum samples and from lung tissues of ...
Jin-Won Song+10 more
doaj +1 more source
Hantaviruses encompass rodent-borne zoonotic pathogens that cause severe hemorrhagic fever disease with high mortality rates in humans. Detection of infectious virus titer lays a solid foundation for virology and immunology researches.
Hong-Wei Ma+10 more
doaj +1 more source
Evaluation and validation on cellular immunoreactivity of Hantaan virus Gc
Objective To screen, identify and verify the immunoreactive epitopes on Hantaan virus glycoprotein C-terminal (HTNV Gc). Methods On the basis of predicting the major histocompatibility complex (MHC) gene in more than 98% of the global population, the ...
XIE Mingyang+4 more
doaj +1 more source