Results 71 to 80 of about 8,666 (240)

Two Point Mutations in Old World Hantavirus Glycoproteins Afford the Generation of Highly Infectious Recombinant Vesicular Stomatitis Virus Vectors

open access: yesmBio, 2019
Rodent-to-human transmission of hantaviruses is associated with severe disease. Currently, no FDA-approved, specific antivirals or vaccines are available, and the requirement for high biocontainment (biosafety level 3 [BSL-3]) laboratories limits ...
Megan M. Slough   +2 more
doaj   +1 more source

Improving the identification of antigenic sites in the H1N1 Influenza virus through accounting for the experimental structure in a sparse hierarchical Bayesian model [PDF]

open access: yesJ. R. Stat. Soc. C (2019), 2017
Understanding how genetic changes allow emerging virus strains to escape the protection afforded by vaccination is vital for the maintenance of effective vaccines. In the current work, we use structural and phylogenetic differences between pairs of virus strains to identify important antigenic sites on the surface of the influenza A(H1N1) virus through
arxiv   +1 more source

Combating SARS-CoV-2: leveraging microbicidal experiences with other emerging/re-emerging viruses [PDF]

open access: yesPeerJ, 2020
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan City, China, late in December 2019 is an example of an emerging zoonotic virus that threatens public health and international travel and commerce.
M. Khalid Ijaz   +4 more
doaj   +2 more sources

Functional analysis of the Bunyamwera orthobunyavirus Gc glycoprotein [PDF]

open access: yes, 2009
The virion glycoproteins Gn and Gc of Bunyamwera orthobunyavirus (family Bunyaviridae) are encoded by the M RNA genome segment and have roles in both viral attachment and membrane fusion.
Brauburger, K.   +4 more
core   +2 more sources

SARS-CoV-2 Virus-Like Particles with Plasmonic Au Cores and S1-Spike Protein Coronas [PDF]

open access: yesarXiv, 2022
The COVID-19 pandemic has stimulated the scientific world to intensify virus-related studies, aimed at the development of quick and safe ways of detecting viruses in human body, studying the virus-antibody and virus-cell interactions, and designing nanocarriers for targeted antiviral therapies.
arxiv  

Hemorrhagic fever with renal syndrome:pathogenesis and clinical picture

open access: yesFrontiers in Cellular and Infection Microbiology, 2016
Hantaan virus (HTNV) causes hemorrhagic fever with renal syndrome (HFRS), which is a zoonosis endemic in eastern Asia, especially in China. The reservoir host of HTNV is field mouse (Apodemus agraricus).
Hong eJiang   +4 more
doaj   +1 more source

Real-time PCR assay development for the control of vaccine against hemorrhagic fever with renal syndrome

open access: yesВопросы вирусологии, 2021
Introduction. Hemorrhagic fever with renal syndrome (HFRS) holds a leading place among natural focal human diseases in Russian Federation. There is no etiotropic therapy for the disease now. The vaccine prophylaxis is the most effective method to control
M. S. Egorova   +11 more
doaj   +1 more source

Hemorrhagic Fever with Renal Syndrome in 4 US Soldiers, South Korea, 2005

open access: yesEmerging Infectious Diseases, 2009
Four US soldiers acquired hemorrhagic fever with renal syndrome while training near the Demilitarized Zone, South Korea, in 2005. Hantaan virus sequences were amplified by reverse transcription–PCR from patient serum samples and from lung tissues of ...
Jin-Won Song   +10 more
doaj   +1 more source

In-Cell Western Assays to Evaluate Hantaan Virus Replication as a Novel Approach to Screen Antiviral Molecules and Detect Neutralizing Antibody Titers

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Hantaviruses encompass rodent-borne zoonotic pathogens that cause severe hemorrhagic fever disease with high mortality rates in humans. Detection of infectious virus titer lays a solid foundation for virology and immunology researches.
Hong-Wei Ma   +10 more
doaj   +1 more source

Evaluation and validation on cellular immunoreactivity of Hantaan virus Gc

open access: yes陆军军医大学学报, 2023
Objective To screen, identify and verify the immunoreactive epitopes on Hantaan virus glycoprotein C-terminal (HTNV Gc). Methods On the basis of predicting the major histocompatibility complex (MHC) gene in more than 98% of the global population, the ...
XIE Mingyang   +4 more
doaj   +1 more source

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