Results 101 to 110 of about 3,264,582 (283)

Recent Advances in Humoral Immunity Dysregulation in Severe Fever With Thrombocytopenia Syndrome Virus (SFTSV) Infection: A Systematic Review

open access: yesHealth Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aims Severe fever with thrombocytopenia syndrome virus (SFTSV) infection causes profound dysregulation of humoral immunity, leading to immunopathology and impaired viral clearance. However, the mechanisms underlying B cell dysfunction and inadequate antibody responses remain poorly defined.
Hongyan Hou   +5 more
wiley   +1 more source

Structure of the Hantavirus Nucleoprotein Provides Insights into the Mechanism of RNA Encapsidation

open access: yesCell Reports, 2016
Hantaviruses are etiological agents of life-threatening hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome. The nucleoprotein (N) of hantavirus is essential for viral transcription and replication, thus representing an ...
Daniel Olal, Oliver Daumke
doaj   +1 more source

Hemodialysis and Water Management in a Dialysis Unit in Morocco, an Approach to Dealing With Water Scarcity

open access: yesHemodialysis International, Volume 29, Issue 4, Page 647-654, October 2025.
ABSTRACT Introduction Chronic kidney disease is a global public health issue, affecting approximately 10% of the world's population, and more than 3 million people living with kidney failure who are estimated to be on maintenance dialysis programs, with the majority receiving hemodialysis (HD).
I. Haddiya   +5 more
wiley   +1 more source

Hantavirus Infection in the Republic of Georgia

open access: yesEmerging Infectious Diseases, 2009
We describe a laboratory-confirmed case of hantavirus infection in the Republic of Georgia. Limited information is available about hantavirus infections in the Caucasus, although the infection has been reported throughout Europe and Russia.
Tinatin Kuchuloria   +5 more
doaj   +1 more source

The PD-1/PD-L1 Axis and Virus Infections: A Delicate Balance [PDF]

open access: yes, 2019
Programmed cell death protein (PD-1) and its ligands play a fundamental role in the evasion of tumor cells from antitumor immunity. Less well appreciated is the fact that the PD-1/PD-L1 axis also regulates antiviral immune responses and is therefore ...
Raftery, Martin J., Schönrich, Günther
core   +1 more source

Low Thoracic Muscle Mass: A Novel Indicator of Poor Prognosis in Patients With Severe Fever With Thrombocytopenia Syndrome

open access: yesImmunity, Inflammation and Disease, Volume 13, Issue 9, September 2025.
Low thoracic muscle mass is associated with adverse outcomes in patients with severe fever with thrombocytopenia syndrome. Thoracic muscle mass may serve as a reliable prognostic marker for severe fever with thrombocytopenia syndrome in clinical settings.
Xiao‐Min Wang   +7 more
wiley   +1 more source

NK cell activation in human hantavirus infection explained by virus-induced IL-15/IL15Rα expression. [PDF]

open access: yesPLoS Pathogens, 2014
Clinical infection with hantaviruses cause two severe acute diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). These diseases are characterized by strong immune activation, increased vascular permeability, and
Monika Braun   +6 more
doaj   +1 more source

Microevolution of bank voles (Myodes glareolus) at neutral and immune-related genes during multiannual dynamic cycles : Consequences for Puumala hantavirus epidemiology [PDF]

open access: yes, 2017
Understanding howhost dynamics, including variations of population size and dispersal, may affect the epidemiology of infectious diseases through ecological and evolutionary processes is an active research area.
Charbonnel, Nathalie   +10 more
core   +2 more sources

Conserved Endonuclease Function of Hantavirus L Polymerase. [PDF]

open access: yes, 2016
Hantaviruses are important emerging pathogens belonging to the Bunyaviridae family. Like other segmented negative strand RNA viruses, the RNA-dependent RNA polymerase (RdRp) also known as L protein of hantaviruses lacks an intrinsic "capping activity ...
Engler, O.   +4 more
core   +2 more sources

Evaluating the Effectiveness of NOACs and LMWH in Reducing Mortality in Critically Ill Patients With COVID‐19

open access: yesJournal of Medical Virology, Volume 97, Issue 8, August 2025.
ABSTRACT Severe COVID‐19 is associated with increased prothrombotic and inflammatory responses, necessitating effective anticoagulation therapy. Novel oral anticoagulants (NOACs) are being explored as potential alternatives to low‐molecular‐weight heparin (LMWH).
Rubens Carmo Costa‐Filho   +11 more
wiley   +1 more source

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