Results 101 to 110 of about 3,264,582 (283)
ABSTRACT Background and Aims Severe fever with thrombocytopenia syndrome virus (SFTSV) infection causes profound dysregulation of humoral immunity, leading to immunopathology and impaired viral clearance. However, the mechanisms underlying B cell dysfunction and inadequate antibody responses remain poorly defined.
Hongyan Hou +5 more
wiley +1 more source
Structure of the Hantavirus Nucleoprotein Provides Insights into the Mechanism of RNA Encapsidation
Hantaviruses are etiological agents of life-threatening hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome. The nucleoprotein (N) of hantavirus is essential for viral transcription and replication, thus representing an ...
Daniel Olal, Oliver Daumke
doaj +1 more source
ABSTRACT Introduction Chronic kidney disease is a global public health issue, affecting approximately 10% of the world's population, and more than 3 million people living with kidney failure who are estimated to be on maintenance dialysis programs, with the majority receiving hemodialysis (HD).
I. Haddiya +5 more
wiley +1 more source
Hantavirus Infection in the Republic of Georgia
We describe a laboratory-confirmed case of hantavirus infection in the Republic of Georgia. Limited information is available about hantavirus infections in the Caucasus, although the infection has been reported throughout Europe and Russia.
Tinatin Kuchuloria +5 more
doaj +1 more source
The PD-1/PD-L1 Axis and Virus Infections: A Delicate Balance [PDF]
Programmed cell death protein (PD-1) and its ligands play a fundamental role in the evasion of tumor cells from antitumor immunity. Less well appreciated is the fact that the PD-1/PD-L1 axis also regulates antiviral immune responses and is therefore ...
Raftery, Martin J., Schönrich, Günther
core +1 more source
Low thoracic muscle mass is associated with adverse outcomes in patients with severe fever with thrombocytopenia syndrome. Thoracic muscle mass may serve as a reliable prognostic marker for severe fever with thrombocytopenia syndrome in clinical settings.
Xiao‐Min Wang +7 more
wiley +1 more source
NK cell activation in human hantavirus infection explained by virus-induced IL-15/IL15Rα expression. [PDF]
Clinical infection with hantaviruses cause two severe acute diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). These diseases are characterized by strong immune activation, increased vascular permeability, and
Monika Braun +6 more
doaj +1 more source
Microevolution of bank voles (Myodes glareolus) at neutral and immune-related genes during multiannual dynamic cycles : Consequences for Puumala hantavirus epidemiology [PDF]
Understanding howhost dynamics, including variations of population size and dispersal, may affect the epidemiology of infectious diseases through ecological and evolutionary processes is an active research area.
Charbonnel, Nathalie +10 more
core +2 more sources
Conserved Endonuclease Function of Hantavirus L Polymerase. [PDF]
Hantaviruses are important emerging pathogens belonging to the Bunyaviridae family. Like other segmented negative strand RNA viruses, the RNA-dependent RNA polymerase (RdRp) also known as L protein of hantaviruses lacks an intrinsic "capping activity ...
Engler, O. +4 more
core +2 more sources
ABSTRACT Severe COVID‐19 is associated with increased prothrombotic and inflammatory responses, necessitating effective anticoagulation therapy. Novel oral anticoagulants (NOACs) are being explored as potential alternatives to low‐molecular‐weight heparin (LMWH).
Rubens Carmo Costa‐Filho +11 more
wiley +1 more source

