Results 41 to 50 of about 5,915 (170)
With the immensely growing outbreaks of hantavirus with still no effective treatment available, there is an urgent need of exploring new computational approaches which will target potential virulent proteins that will eventually reduce its growth.
Abdulrahman Alshammari
doaj +1 more source
Understanding the ecology of rodent-borne hantaviruses is critical to assessing the risk of spillover to humans. Longitudinal surveys have suggested that hantaviral prevalence in a given host population is tightly linked to rodent ecology and correlates ...
Jeremy V. Camp +7 more
doaj +1 more source
Plasma Exchange for Hantavirus Pulmonary Syndrome: A Mechanistic Case for an Untested Intervention
ABSTRACT Hantavirus pulmonary syndrome (HPS) carries a case fatality rate of 35%–40% and has no approved pharmacologic treatment. Its pathophysiology is rooted in the plasma compartment: cytokines, viral antigens, immune complexes, and platelet‐binding glycoproteins circulate as drivers of immunopathologic endothelial injury, noncardiogenic pulmonary ...
Menatalla Nadim +2 more
wiley +1 more source
Identification of tell-tale patterns in the 3′ non-coding region of hantaviruses that distinguish HCPS-causing hantaviruses from HFRS-causing ...
Jayanta Borkakoti (6540179) +5 more
core +1 more source
Coumarin Derivative N6 as a Novel anti-hantavirus Infection Agent Targeting AKT
Hantaviruses are globally emerging zoonotic viruses that can cause hemorrhagic fever with renal syndrome (HFRS) in Asia and Europe, which is primarily caused by Hantaan virus (HTNV) infection, results in profound morbidity and mortality.
Zhoupeng Li +12 more
doaj +1 more source
Beyond the Kidney and Lung: Cutaneous and Mucosal Clues to Human Hantavirus Disease
Rodent exposure and aerosolized excreta can lead to hantavirus infection with systemic endothelial injury and capillary leak, resulting in thrombocytopenia and syndromes such as HPS/HCPS and HFRS/NE. Early dermatologic and mucosal findings, including flushing, conjunctival injection, petechiae/purpura, and mucosal bleeding, may provide important clues ...
Giuseppe Gallo +2 more
wiley +1 more source
“The Power of We” is a personal tribute to the individuals and organizations that collaborated in the discovery and advancement of knowledge of the hantaviruses following the original isolation of Hantaan virus by Ho Wang Lee. It focuses on the work done
James W. Le Duc
doaj +1 more source
Expanded host diversity and geographic distribution of hantaviruses in sub-Saharan Africa [PDF]
The recent discovery of hantaviruses in shrews and bats in West Africa suggests that other genetically distinct hantaviruses exist in East Africa. Genetic and phylogenetic analyses of newfound hantaviruses, detected in archival tissues from the Geata ...
Stanley, William T. +4 more
core +1 more source
ABSTRACT Cruise ships and other confined travel settings remain highly vulnerable to infectious disease outbreaks. During 2025–2026, multiple norovirus outbreaks and the rare Andes hantavirus outbreak associated with the MV Hondius cruise highlighted the continuing public health challenges posed by both highly transmissible enteric viruses and emerging
Umme Laila Urmi, Mark D. P. Willcox
wiley +1 more source
Conserved Endonuclease Function of Hantavirus L Polymerase
Hantaviruses are important emerging pathogens belonging to the Bunyaviridae family. Like other segmented negative strand RNA viruses, the RNA-dependent RNA polymerase (RdRp) also known as L protein of hantaviruses lacks an intrinsic “capping activity ...
Sylvia Rothenberger +4 more
doaj +1 more source

