Results 41 to 50 of about 141,394 (267)
Doubled haploid ramets via embryogenesis of haploid tissue cultures [PDF]
Tissue culture in the oil palm business is generally concerned with the multiplication (clonal production) of dura, pisifera and tenera palms. These are all normal diploids (2n=2x=36).
Caligari, P. D. S. +4 more
core
Semiconservative quasispecies equations for polysomic genomes: The general case
This paper develops a formulation of the quasispecies equations appropriate for polysomic, semiconservatively replicating genomes. This paper is an extension of previous work on the subject, which considered the case of haploid genomes.
C. S. Potten +4 more
core +1 more source
Invertible defects and isomorphisms of rational CFTs [PDF]
Given two two-dimensional conformal field theories, a domain wall —or defect line— between them is called invertible if there is another defect with which it fuses to the identity defect.
Davydov, Alexei +2 more
core +3 more sources
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
The development of in vitro haploid plants followed by spontaneous or induced genome duplication allows to achieve, in one generation, the recovery of total homozygosis. The efficiency of the haplodiploidization process through in vitro anther culture of
Paula Wiethölter +4 more
doaj +1 more source
Discovery and genotyping of structural variation from long-read haploid genome sequence data [PDF]
In an effort to more fully understand the full spectrum of human genetic variation, we generated deep single-molecule, real-time (SMRT) sequencing data from two haploid human genomes.
Boitano, Matthew +15 more
core +2 more sources
Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang +22 more
wiley +1 more source
Double-seedlings and embryo-free seeds generated by genetic engineering
Apomixis can fix the heterosis of Hybrid F1, by maintaining its heterozygous genotype, and is an ideal way for the development of hybrid rice. In this paper, we designed an engineering strategy for realizing apomictic reproduction of hybrid rice in the ...
Yumei Xia +11 more
doaj +1 more source
Mitotic antipairing of homologous and sex chromosomes via spatial restriction of two haploid sets. [PDF]
Pairing homologous chromosomes is required for recombination. However, in nonmeiotic stages it can lead to detrimental consequences, such as allelic misregulation and genome instability, and is rare in human somatic cells.
Hua, Lisa L, Mikawa, Takashi
core +1 more source
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng +16 more
wiley +1 more source

