Results 331 to 340 of about 407,509 (363)

Haplotype Inference Constrained by Plausible Haplotype Data

IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2009
The haplotype inference problem (HIP) asks to find a set of haplotypes which resolve a given set of genotypes. This problem is important in practical fields such as the investigation of diseases or other types of genetic mutations. In order to find the haplotypes which are as close as possible to the real set of haplotypes that comprise the genotypes ...
Michael R, Fellows, Tzvika, Hartman, Danny, Hermelin, Gad M, Landau, Frances, Rosamond, Liat, Rozenberg   +5 more
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Haplotype Inference

2011
Haplotypes, as they specify linkage patterns between individual nucleotide variants, confer critical information for understanding the genetics of human diseases. However, haplotype information is not directly obtainable from high-throughput genotyping platforms.
Xin, Li, Jing, Li
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Ancestral haplotypes: conserved population MHC haplotypes

Human Immunology, 1992
We describe here a number of Caucasoid MHC haplotypes that extend from HLA-B to DR and that have been conserved en bloc. These haplotypes and recombinants between any two of them account for 73% of unselected haplotypes in our Caucasoid population. The existence of ancestral haplotypes implies conservation of large chromosomal segments. Irrespective of
M A, Degli-Esposti, A L, Leaver, F T, Christiansen, C S, Witt, L J, Abraham, R L, Dawkins   +5 more
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Haplotype Inference

2012
The information carried by combination of alleles on the same chromosome, called haplotypes, is of crucial interest in several fields of modern genetics as population genetics or association studies. However, this information is usually lost by sequencing and needs, therefore, to be recovered by inference.
Olivier, Delaneau, Jean-François, Zagury   +1 more
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Haplotype Inference

2017
Haplotypes, as they specify linkage patterns between individual nucleotide variants, confer critical information for understanding the genetics of human diseases. However, haplotype information is not directly obtainable from high-throughput genotyping platforms.
Sunah, Song, Xin, Li, Jing, Li
openaire   +2 more sources

An Algorithm for Haplotype Analysis

Journal of Computational Biology, 1997
This paper proposes an algorithm for haplotype analysis based on a Monte Carlo method. Haplotype configurations are generated according to the distribution of joint haplotypes of individuals in a pedigree given their phenotype data, via a Markov chain Monte Carlo algorithm.
S, Lin, T P, Speed
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Haplotype Inference and Haplotype Information

2004
Haplotypes have become increasingly popular because of the abundance of single nucleotide polymorphisms (SNPs) and the limited power of the single-locus analyses. To contend with some weaknesses of the existing haplotype inference methods, we propose new algorithms based on the partition-ligation idea.
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The MHC haplotypes of the chicken

Immunogenetics, 1982
The major histocompatibility complex (MHC) of Gallus gallus is the B complex of which three classes of cell-membrane antigens have been clearly defined by serological, histogenetic, and biochemical methods. Two of these classes are homologous to classes I and II of mammals (B-F and B-L, respectively), while the third (B-G) is a differentiation antigen ...
M, Simonsen, M, Crone, C, Koch, K, Hála
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