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Algorithms for inferring haplotypes
Genetic Epidemiology, 2004AbstractHaplotype phase information in diploid organisms provides valuable information on human evolutionary history and may lead to the development of more efficient strategies to identify genetic variants that increase susceptibility to human diseases. Molecular haplotyping methods are labor‐intensive, low‐throughput, and very costly.
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Haplotyping as Perfect Phylogeny
2004We consider the following problem: Given n genotypes, does there exist a set H of haplotypes such that each genotype is generated by a pair from this set, and this det can be derived on a perfect phylogeny. Recently, Gusfield, 2002, presented a polynomial time algorithm to solve this problem that uses established results from matroid and graph theory ...
Bafna V. +3 more
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Detecting recent positive selection in the human genome from haplotype structure
Nature, 2002Pardis C Sabeti +16 more
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High-resolution haplotype structure in the human genome
Nature Genetics, 2001M. Daly +4 more
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