Results 121 to 130 of about 127,421 (299)

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

open access: yesIbrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen   +10 more
wiley   +1 more source

Influence of SLA haplotype on ovulation rate and litter size in miniature pigs [PDF]

open access: bronze, 1988
Alan J. Conley   +5 more
openalex   +1 more source

Linkage disequilibrium score regression identifies genetic correlations between hepatocellular carcinoma and clinically relevant traits

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Hepatocellular carcinoma arises from a combination of environmental and genetic factors, with the latter playing a potentially more significant role in nonviral hepatocellular carcinoma. Here, the authors characterized the genetic correlations and heritability between nonviral hepatocellular carcinoma and 901 epidemiologic, behavioral, and ...
Younghun Han   +37 more
wiley   +1 more source

New cell lines expanding the diversity of Ewing sarcoma models

open access: yesInternational Journal of Cancer, EarlyView.
What's New? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff   +13 more
wiley   +1 more source

DNA Barcoding Reveals Cryptic Diversity and Informs Conservation Priorities in Chinese Firmiana Species (Malvaceae) Using Genome Skimming Data DNA条形码揭示中国梧桐属 (锦葵科) 隐存多样性及保护优先级:来自基因组浅层测序数据的证据

open access: yesIntegrative Conservation, EarlyView.
Accurate species identification is critical for conserving endangered Firmiana trees in China. However, morphological similarities among closely related Firmiana species complicate its taxonomic identification. We conducted genome skimming on 62 samples representing all 10 Chinese species and discovered nrITS as the optimal DNA barcode, achieving 100 ...
Li‐Jun Yan   +8 more
wiley   +1 more source

In Vitro Assessment of Drug‐Induced Liver Injury Using Three‐Dimensional Cultured HepaSH Cells Derived From Chimeric Mouse Model With Humanized Liver

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Drug‐induced liver injury (DILI) is a serious adverse event and a common cause of postmarketing drug withdrawal. Despite nonclinical assessments of DILI risk, which are predominantly conducted in experimental animals, DILI remains a frequent adverse event, highlighting the need to improve nonclinical assessments.
Xingming Liu   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy