Results 121 to 130 of about 229,423 (345)

Real‐world study on fluoropyrimidine‐related toxicity outcomes in cancer patients with select DPYD variant alleles that received DPYD genotype‐guided dosing

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Fluoropyrimidines, a key component of chemotherapy regimens for a variety of solid tumors, can cause severe toxicity. Patients who have specific genetic variants in the DPYD gene, which encodes an enzyme that inactivates fluoropyrimidines, have increased susceptibility to this toxicity.
Sofía L. J. Peeters   +12 more
wiley   +1 more source

New Chloroplast Microsatellites in Helichrysum italicum (Roth) G. Don: Their Characterization and Application for the Evaluation of Genetic Resources

open access: yesPlants
Helichrysum italicum (Roth) G. Don is a Mediterranean medicinal plant with great potential in the cosmetics, culinary and pharmaceutical fields due to its unique bioactive compounds.
Matjaž Hladnik   +6 more
doaj   +1 more source

ADAR1 mRNA quantification for predicting HSIL in persons with HIV and abnormal anal cytology

open access: yesInternational Journal of Cancer, EarlyView.
What's New? This study introduces ADAR1 mRNA quantification as a promising biomarker for improving high‐grade squamous intraepithelial lesion (HSIL) prediction in HIV‐positive individuals with abnormal anal cytology. With 92% specificity, it reduces unnecessary high‐resolution anoscopies (HRA) by 77%, offering a more efficient and targeted screening ...
Melissa Bello‐Perez   +15 more
wiley   +1 more source

TOMM40 and APOC1 variants differentiate the impacts of the APOE ε4 allele on Alzheimer's disease risk across sexes, ages, and ancestries

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION The variability in apolipoprotein E (APOE) ε4‐attributed susceptibility to Alzheimer's disease (AD) across ancestries, sexes, and ages may stem from the modulating effects of other genetic variants.
Alexander M. Kulminski   +5 more
doaj   +1 more source

Influence of SLA haplotype on ovulation rate and litter size in miniature pigs [PDF]

open access: bronze, 1988
Alan J. Conley   +5 more
openalex   +1 more source

Haplotype‐resolved genome and pan‐genome graphs reveal the impacts of structural variation on functional genome and feather colors in chickens

open access: yesiMetaOmics, EarlyView.
This study built a Wenchang chicken haplotype genome and integrated it with 29 others to create a chicken pangenome atlas. Analysis of 354 chickens revealed 185,205 structural variations (SVs), with one‐third derived from homology‐based and transposable elements.
Lihong Gu   +9 more
wiley   +1 more source

Genetic Diversity and Phylogeographic Structure of the Edible Caterpillars of Gynanisa maja and Implications for the Sustainability of the Species in Namibia

open access: yesIntegrative Conservation, EarlyView.
Assessing the genetic diversity of edible insects harvested from the wild is a pre‐requisite for designing conservation and management policies. The caterpillars of Gynanisa maja (Saturniidae) are harvested in large numbers in mopane woodlands in southern Africa, where they represent a seasonal source of income and nutrition to many rural communities ...
Zwannda Nethavhani   +3 more
wiley   +1 more source

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