Results 151 to 160 of about 256,625 (325)

A Genome‐Wide Association Study of Colorectal Cancer Mortality Outcomes Among Individuals of African and Admixture Ancestry

Molecular Carcinogenesis, EarlyView.
ABSTRACT African Americans have the highest colorectal cancer (CRC) mortality rates in the United States. We performed the first genome‐wide association study (GWAS) of overall and CRC‐specific mortality among African Americans with incident CRC to identify genetic contributors to CRC outcomes.
Thomas Lawler, Jirong Long, Rene Welch, Irene Ong, Oluwatoyosi Ogunmuyiwa, Rida A. Khatri, Martha Shrubsole, Shaneda Warren Andersen   +7 more
wiley   +1 more source

Genotypes and haplotypes of matrix metalloproteinase 1, 3 and 12 genes and the risk of lung cancer [PDF]

, 2005
Li Su, Wei Zhou, Kofi Asomaning, Xihong Lin, John C. Wain, Thomas J. Lynch, Geoffrey Liu, David C. Christiani   +7 more
openalex   +1 more source

Huntington's Disease and Huntington's Disease‐like 2 (HDL2) in Martinique

Movement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Huntington's Disease‐like 2 (HDL2), caused by a CAG repeat expansion in JPH3, closely resembles HD. All reported HDL2 patients to date have some African ancestry. While both disorders exist in the Caribbean, their relative frequency and clinical characteristics remain largely unknown.
Ignacio Antolin‐Sanfeliz, Anna‐Gaelle Giguet‐Valard, Sophie Duclos, Cécile Cazeneuve, Chloé Angelini, Aïssatou Signaté, Russell L. Margolis, Cyril Goizet, Rémi Bellance   +8 more
wiley   +1 more source

Polymorphisms and Haplotypes of the <i>CD209L</i> Gene and Their Association with the Clinical Courses of HIV-Positive Japanese Patients

, 2002
Noriko Kobayashi, Hitomi Taguchi-Nakamura, Mieko Goto, Tetsuya Nakamura, Koichiro Nakamura, Wataru Sugiura, Aikichi Iwamoto, Yoshihiro Kitamura   +7 more
openalex   +2 more sources

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

OR22 HLA-G regulatory and coding region haplotypes in papillary thyroid carcinoma

, 2018
Bruna C. Bertol, Guilherme Debortoli, Fabrício C. Dias, Jéssica Nayara Góes de Araújo, Nathalie L. de Figueiredo-Feitosa, Vivian Nogueira Silbiger, Celso Teixeira Mendes‐Junior, Erick C. Castelli, Léa Maria Zanini Maciel, Eduardo Antônio Donadi   +9 more
openalex   +2 more sources

A Monte Carlo Approach for Estimation of Haplotype Probabilities in Half-Sib Families [PDF]

, 2004
P. Boettcher, G. Pagnacco, Alessandra Stella   +2 more
openalex   +1 more source

Integrating Long‐Read Nanopore Sequencing for Precision Resolution of Genomic Variants in Dystonia

Movement Disorders, EarlyView.
Abstract Background Although many individuals with dystonia present with features indicative of single‐gene etiologies, obtaining definitive genetic diagnoses can be challenging. Objective We assessed the value of nanopore‐based long‐read sequencing (LRS) in achieving molecular clarification of dystonic syndromes.
Ugo Sorrentino, Martin Pavlov, Nazanin Mirza‐Schreiber, Melanie Brugger, Theresa Brunet, Eugenia Tsoma, Alice Saparov, Ivana Dzinovic, Philip Harrer, Antonia M. Stehr, Matias Wagner, Erik Tilch, Barbara Wallacher, Shiraz Alhasan, Anne Koy, Alessio Di Fonzo, Miriam Kolnikova, Katarina Kusikova, Petra Havrankova, Raushana Tautanova, Sandy Lösecke, Sebastian Eck, Sylvia Boesch, Jan Necpal, Matej Skorvanek, Robert Jech, Holger Prokisch, Juliane Winkelmann, Konrad Oexle, Elisabeth Graf, Michael Zech   +30 more
wiley   +1 more source

Comparison of Greek Sardina pilchardus haplotypes with those found in the global distribution of the species, for characterization of the Greek populations as Protective Geographic Indication (PGI) products

, 2019
Anastasia Imsiridou, SOFIA KARNEZI, George Minos   +2 more
openalex   +1 more source

Characterisation of SNP haplotype structure in chemokine and chemokine receptor genes using CEPH pedigrees and statistical estimation [PDF]

, 2004
Vanessa J. Clark, Michael Dean
openalex   +1 more source