Results 151 to 160 of about 229,423 (345)

Identifying Common Disease Trajectories of Progressive Supranuclear Palsy with Electronic Health Records

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Progressive supranuclear palsy (PSP) is a rare neurodegenerative disorder characterized by parkinsonism and impairments in balance, language, and cognition. As an atypical parkinsonism, PSP progresses rapidly, lacks effective treatments, and poses significant caregiving burdens. While prior studies have identified risk factors, they
Mingzhou Fu, Sriram Sankararaman, Keith A Vossel, Timothy S. Chang   +3 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

IgD allotypic determinants. II. Determinants expressed on IgD of mice of the b, e, and o Igh-C haplotypes. [PDF]

, 1980
V L Woods, I Scher, R Lieberman, W E Paul   +3 more
openalex   +1 more source

EFNB3 Frameshift Variant in Weimaraner Dogs with a Condition Resembling a Congenital Mirror Movement Disorder

Movement Disorders, EarlyView.
ABSTRACT Background Congenital mirror movement disorders (CMMs) are clinically and genetically heterogeneous in human patients. CMMs have not been documented to occur spontaneously in animals. Objective The objective of this work was to document the first case of CMMs spontaneously occurring in Weimaraner dogs and to identify the underlying genetic ...
Cleo Schwarz, Florian Bartenschlager, Olivia Kershaw, Judith Braun, Julien Guevar, Vidhya Jagannathan, Jörg T. Epplen, Wencke Reineking, Wolfgang Baumgärtner, Kailash P. Bhatia, Achim D. Gruber, Tosso Leeb   +11 more
wiley   +1 more source

19 EVIDENCE FOR RECOMBINED HAPLOTYPES IN THE AREA OF THE 21-HYDROXYLASE (21-OHase) A- AND B GENE IN CONGENITAL ADRENAL HYPERPLASIA (CAH) [PDF]

, 1988
Sigrid Janssen, D Knorr, K. Olek, Konstanze D. Römer, F. Bidlingmaier   +4 more
openalex   +1 more source

Class I HLA haplotypes form two schools that educate NK cells in different ways

Science immunology, 2016
A. Horowitz, Zakia Djaoud, Neda Nemat-Gorgani, J. Blokhuis, H. Hilton, V. Béziat, Karl-Johan Malmberg, P. Norman, L. Guethlein, P. Parham   +9 more
semanticscholar   +1 more source

A CGG Repeat Expansion in CSNK1E Associated with Progressive Myoclonic Epilepsy with Incomplete Penetrance

Movement Disorders, EarlyView.
Abstract Background Progressive myoclonic epilepsy is a heterogeneous neurodegenerative disorder characterized by early‐onset myoclonus, epilepsy, generalized tonic–clonic seizures, and progressive neurological deterioration. Recently, a CGG repeat expansion and increased CSNK1E DNA methylation have been shown to be associated with developmental and ...
Fulya Akçimen, Pilar Alvarez Jerez, Ulviyya Guliyeva, Jasmine Lee, Laksh Malik, Breeana Baker, Kamran Salayev, Sughra Guliyeva, Kimberley J. Billingsley, Henry Houlden, Andrew B. Singleton, Cornelis Blauwendraat, Sara Bandres‐Ciga, Rauan Kaiyrzhanov   +13 more
wiley   +1 more source

PROTRACTED DIARRHOEA AND AUTOIMMUNE ENTEROPATHY: A GENERALISED AUTOIMMUNE GUT DISORDER WITH A COMMON HLA HAPLOTYPE [PDF]

, 1989
S. Hill, Rita Mirakian, Peter J. Milla
openalex   +1 more source

Experimental Support That Natural Selection Has Shaped the Latitudinal Distribution of Mitochondrial Haplotypes in Australian Drosophila melanogaster

Molecular biology and evolution, 2017
M. Camus, J. Wolff, C. Sgrò, D. Dowling
semanticscholar   +1 more source

Arbuscular mycorrhizal fungal genotype and nuclear organization as driving factors in host plant nutrient acquisition and stable carbon storage

PLANTS, PEOPLE, PLANET, EarlyView.
It is crucial to develop strategies for reducing our continued excessive global increases in fertilizer applications and to offset CO2 emissions. The pervasive underground hyphal networks of arbuscular mycorrhizal fungi (AMF) present an enticing bio‐stimulant and carbon sink. We inoculated Sudan‐grass plants with eight genotypically distinct strains of
Robert Ferguson, Ken Mugambi, Matthew Villeneuve‐Laroche, Cynthia M. Kallenbach, Pedro M. Antunes, Nicolas Corradi   +5 more
wiley   +1 more source