Results 301 to 310 of about 350,738 (380)

Long‐term cardiovascular risk in women with hypertensive disorders of pregnancy: Insights from polygenic risk scores

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
FinnGen data of 213 942 women was utilized in order to investigate the risk of cardiovascular disease in women with and without hypertensive disorders of pregnancy and with diverse genetic risks for cardiovascular disease and preeclampsia measured with polygenic risk scores.
Anna Kivioja, Jaakko Tyrmi, Elli Toivonen, Heini Huhtala, FinnGen, Tiina Jääskeläinen, Johannes Kettunen, Tanja Saarela, Hannele Laivuori   +8 more
wiley   +1 more source

Nearly T2T, phased genome assemblies of corals reveal haplotype diversity and the evolutionary process of gene expansion. [PDF]

DNA Res
Takeuchi T, Suzuki Y, Shoguchi E, Fujie M, Kawamitsu M, Shinzato C, Satoh N, Myers EW.   +7 more
europepmc   +1 more source

Human amyotrophic lateral sclerosis/motor neuron disease: The disease‐associated microglial pathway is upregulated while APOE genotype governs risk and survival

Brain Pathology, EarlyView.
ALS/MND‐related inflammation is investigated in the motor cortex and spinal cord by both transcriptomics and immunohistochemistry. This reveals greater inflammation in the spinal cord and highlights the disease‐associated microglial (DAM) phenotype characterized by ApoE, TREM2, and TYROBP.
Bridget A. Ashford, Julie E. Simpson, Charlotte Dawson, Delphine Boche, Johnathan Cooper‐Knock, Paul R. Heath, Daniel Fillingham, Charlie Appleby‐Mallinder, Wenbin Wei, Mark Dunning, J. Robin Highley   +10 more
wiley   +1 more source

Advances in grape and pathogen genomics toward durable grapevine disease resistance. [PDF]

J Exp Bot
Paineau M, Zaccheo M, Massonnet M, Cantu D.   +3 more
europepmc   +1 more source

Haplotype Construction of Sires with Progeny Genotypes Based on an Exact Likelihood

, 1998
F.-X. Du, B. W. Woodward, S. K. DeNise
openalex   +1 more source

Novel approaches for the discovery of pharmacogenetic biomarkers of chemotoxicity in patients with colorectal cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Chemotherapeutic treatment for colorectal cancer (colorectal cancer) allows for increased patient overall survival. However, current therapeutic regimens are often associated with the development of adverse drug reactions, which represent a morbidity, mortality and economic issue.
Ana Rita Simoes, Silvia Carlés González, María del Carmen Lopez‐Doldan, Goretti Duran, Ana Fernández‐Montes, Maria Perfecta Fernandez, Mercedes Salgado Fernandez, Jesus Garcia Mata, David Paez, Pau Riera, Elisabeth Guino, Luis Lopez‐Fernandez, Belen Garcia de Santiago, Elena López Aspiroz, Augusto Rojas, Antoni Castells, Sergi Castellvi‐Bel, Clara Ruiz Ponte, Veronika Vymetalkova, Angel Carracedo, Ceres Fernandez‐Rozadilla   +20 more
wiley   +1 more source

Occurrence and Genetic Variation of <i>Monolepta hieroglyphica</i> (Motschulsky, 1858) (Coleoptera: Chrysomelidae), a Newly Emerging Pest, Among Hosts in Northeast China. [PDF]

Insects
Sun W, Zhang X, Zhou J, Gao Y.
europepmc   +1 more source

HLA GENE AND HAPLOTYPE FREQUENCIES IN THE NORTH AMERICAN POPULATION

, 1997
Motomi Mori, Patrick G. Beatty, Michael C. Graves, Kenneth M. Boucher, Edgar L. Milford   +4 more
openalex   +1 more source

The Diverse Genetic Landscape of Hearing Impairment in South African Families

Clinical Genetics, EarlyView.
South African Families with Nonsyndromic (N = 24) and Syndromic Hearing Impairment (N = 21) with ≥ 2 affected members were analyzed. The underlying etiology was uncovered using exome and Sanger sequencing for 31 of these families. ABSTRACT To elucidate the genetic etiology of hearing impairment (HI) in South Africa, 45 nonsyndromic HI (NSHI) and ...
Thashi Bharadwaj, Anushree Acharya, Noluthando Rearabetswe Manyisa, Elvis Twumasi Aboagye, Ramses Peigou Wonkam, Lettilia Xhakaza, Kalinka Popel, Carmen de Kock, Isabelle Schrauwen, Ambroise Wonkam, Suzanne M. Leal   +10 more
wiley   +1 more source