Results 81 to 90 of about 256,625 (325)
Geographic variation and evolutionary history of Dipodomys nitratoides (Rodentia: Heteromyidae), a species in severe decline [PDF]
, 2019 We examined geographic patterns of diversification in the highly impacted San Joaquin kangaroo rat, Dipodomys nitratoides, throughout its range in the San Joaquin Valley and adjacent basins in central California.
Cypher, BL +4 more
core
, 2003 Intestinal cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (P-gp) both play a vital role in the metabolism of oral cyclosporine (CsA). We investigated the genetic polymorphisms in CYP3A4(promoter region and exons 5, 7 and 9) and MDR1 (exons 12, 21 and 26)
Cheung, Yin Bun +4 more
core +1 more source
High-throughput haplotype determination over long distances by haplotype fusion PCR and ligation haplotyping [PDF]
Nature Protocols, 2009 When combined with haplotype fusion PCR (HF-PCR), ligation haplotyping is a robust, high-throughput method for empirical determination of haplotypes, which can be applied to assaying both sequence and structural variation over long distances. Unlike alternative approaches to haplotype determination, such as allele-specific PCR and long PCR, HF-PCR and ...
Daniel J, Turner, Matthew E, Hurles
openaire +2 more sources
Homozygosity Haplotype and Whole-Exome Sequencing Analysis to Identify Potentially Functional Rare Variants Involved in Multiple Sclerosis among Sardinian Families [PDF]
, 2021 Teresa Fazia +9 more
openalex +1 more source
Annals of Neurology, EarlyView.Objective Behavior and motor manifestations are distinctive yet often overlooked features of epileptic seizures. Seizures can result in transient disruptions in motor control, often organized into specific behavioral sequences that can inform seizure types, onset zones, and outcomes.
Yuyan Shen +8 more
wiley +1 more source
Perfect phylogeny haplotyper: haplotype inferral using a tree model [PDF]
Bioinformatics, 2003 Abstract Summary: We have developed an efficient program, the Perfect Phylogeny Haplotyper (PPH) that takes in unphased population genotype data, and determines if that data can be explained by haplotype pairs that could have evolved on a perfect phylogeny.
Ren Hua, Chung, Dan, Gusfield
openaire +2 more sources
Annals of Neurology, EarlyView.Objective Lewy body disease (LBD) is a complex neurodegenerative disorder characterized by the accumulation of misfolded α‐synuclein in the brain. Neuroinflammation has long been implicated in LBD pathogenesis, and recent genetic studies in Parkinson's disease (a clinical manifestation of LBD) have shown consistent association with the human leukocyte ...
Marios Gavrielatos +34 more
wiley +1 more source
Systematics of the North American menhadens: molecular evolutionary reconstructions in the genus Brevoortia (Clupeiformes: Clupeidae) [PDF]
, 2007 Evolutionary associations among the four North American species of menhadens (Brevoortia spp.) have not been thoroughly investigated. In the present study, classifications separating the four species into small-scaled and large-scaled groups were ...
Anderson, Joel D.
core
Wandering behaviour prevents inter and intra oceanic speciation in a coastal pelagic fish [PDF]
, 2017 Small pelagic fishes have the ability to disperse over long distances and may present complex evolutionary histories. Here, Old World Anchovies (OWA) were used as a model system to understand genetic patterns and connectivity of fish between the Atlantic
A Magoulas +51 more
core +2 more sources
Annals of Neurology, EarlyView.Objective Whether cognitive decline in patients with Parkinson's disease (PD) carrying GBA1 variants is accelerated after subthalamic deep brain stimulation (STN‐DBS) remains controversial. Clarifying long‐term cognitive outcomes is essential for informed decision making.
Moritz A. Loeffler +8 more
wiley +1 more source