Results 81 to 90 of about 229,423 (345)

GmSop20 Functions as a Key Coordinator of the Oil‐To‐Protein Ratio in Soybean Seeds

open access: yesAdvanced Science, EarlyView.
This study investigates the seed oil‐to‐protein ratio as a comprehensive quality metric and identifies GmSop20 as a crucial regulatory gene through forward genetics methodologies. By integrating GmSop20 with superior haplotypes and using gene editing/overexpression, new strategies are provided for precisely tuning the seed oil‐to‐protein ratio, thereby
Haowei Zheng   +17 more
wiley   +1 more source

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.

open access: yesBlood, 2009
Survival for patients with acute myeloid leukemia (AML) is limited by treatment-related mortality (TRM) and relapse after unrelated donor (URD) hematopoietic cell transplantation (HCT).
S. Cooley   +10 more
semanticscholar   +1 more source

Subgenome Partitioning and Polyploid Genome Evolution in the Loach Family Botiidae (Order Cypriniformes)

open access: yesAdvanced Science, EarlyView.
This study investigates subgenome evolution and polyploidy in Cypriniformes fish, revealing complex phylogenetic relationships and genomic dynamics. By applying advanced subgenome partitioning methods, it uncovers novel insights into transposon activity and gene fractionation.
Yunyun Lv   +14 more
wiley   +1 more source

Inference of haplotypes from PCR-amplified samples of diploid populations.

open access: yesMolecular biology and evolution, 1990
Direct sequencing of genomic DNA from diploid individuals leads to ambiguities on sequencing gels whenever there is more than one mismatching site in the sequences of the two orthologous copies of a gene. While these ambiguities cannot be resolved from a
A. Clark
semanticscholar   +1 more source

Manipulating Unisexual–Sexual Reproduction Transition to Engineer Genome‐Reconstructed Polyploids

open access: yesAdvanced Science, EarlyView.
This study developed an efficient approach to generate genome‐reconstructed polyploids involving unisexual gynogenetic Carassius gibelio, sexual C. auratus, and sexual C. cuvieri. The selected superior clone inherited gynogenesis ability of C. gibelio and herpesvirus resistance of wild C.
Meng Lu   +9 more
wiley   +1 more source

Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids.

open access: yesHuman Molecular Genetics, 2006
Fatty acid composition in membranes plays an important role in cellular processes and has shown to be associated with the aetiology of several complex diseases in humans.
Linda Schaeffer   +9 more
semanticscholar   +1 more source

A Random Forests Framework for Modeling Haplotypes as Mosaics of Reference Haplotypes

open access: yesFrontiers in Genetics, 2019
Many genomic data analyses such as phasing, genotype imputation, or local ancestry inference share a common core task: matching pairs of haplotypes at any position along the chromosome, thereby inferring a target haplotype as a succession of pieces from reference haplotypes, commonly called a mosaic of reference haplotypes.
Faux, Pierre, Geurts, Pierre, Druet, Tom
openaire   +5 more sources

Haplotypes versus Genotypes on Pedigrees [PDF]

open access: yesAlgorithms for Molecular Biology, 2010
Genome sequencing will soon produce haplotype data for individuals. For pedigrees of related individuals, sequencing appears to be an attractive alternative to genotyping. However, methods for pedigree analysis with haplotype data have not yet been developed, and the computational complexity of such problems has been an open question.
Bonnie Kirkpatrick, Bonnie Kirkpatrick
openaire   +7 more sources

The unique morphological basis and repeated evolutionary origins of personate flowers in Penstemon

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Adaptive radiation in ecologically and morphologically diverse plant lineages presents an opportunity to investigate the rapid evolution of novel floral traits. While some types of floral traits, such as flower color, are well characterized, other types of complex morphologies remain understudied.
Trinity H. Depatie, Carolyn A. Wessinger
wiley   +1 more source

A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping. I. Basic theory and an analysis of alcohol dehydrogenase activity in Drosophila.

open access: yesGenetics, 1987
Because some genes have been cloned that have a known biochemical or physiological function, genetic variation can be measured in a population at loci that may directly influence a phenotype of interest.
Alan R. Templeton   +2 more
semanticscholar   +1 more source

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