Results 101 to 110 of about 778 (210)
Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong +3 more
wiley +1 more source
ABSTRACT In this study, we demonstrate the effects of adopting “imaginary future generations (IFGs),” which has been proven to be effective for generating futurability in individuals, on policy choices and individual attitudes toward environmentally friendly behavior.
Keishiro Hara +2 more
wiley +1 more source
ABSTRACT This paper introduces the Ubuntu Intergenerational Primer (UIP), a culturally grounded cognitive debiasing intervention designed to mitigate future discounting bias among Real‐Time Delphi (RTD) participants in Southern Africa. Learning from prior research engagements and informed by the region's cultural settings, we innovated around the Rip ...
Simbarashe Nhokovedzo +3 more
wiley +1 more source
Single‐nucleus multiomic profiling of postmortem brain reveals coordinated immune, metabolic, and epigenomic reprogramming in glia of people with HIV consistent with maladaptive trained immunity sustaining neuroinflammation in HAND. ABSTRACT HIV‐associated neurocognitive disorders (HAND) remain prevalent in people with HIV (PWH) despite effective ...
Siera Martinez +8 more
wiley +1 more source
Palliative Approach to Care Education for Multidisciplinary Staff of Long-Term Care Homes: A Pretest Post-Test Study. [PDF]
Vellani S +6 more
europepmc +1 more source
Abstract Background Lattice radiotherapy (LRT) is a spatially fractionated technique that delivers three‐dimensional high‐dose vertices within tumors. However, conventional LRT is constrained by geometric limitations when applied to small and medium‐sized tumor volumes, primarily due to the large beam sizes that restrict optimal lattice pattern ...
Wei Wu +7 more
wiley +1 more source
Hematopoietic stem cell mobilization for allogeneic stem cell transplantation by motixafortide, a novel CXCR4 inhibitor. [PDF]
Crees ZD +14 more
europepmc +1 more source
Abstract F1‐ATPase (F1) is a rotary molecular motor that hydrolyzes adenosine triphosphate (ATP) to drive rotation of the central subunit against the surrounding stator ring. Single‐molecule rotation assays of mutated F1s have elucidated the roles of residues and regions in the chemo‐mechanical coupling mechanism, yet comprehensive mutational ...
Mai Taguchi +3 more
wiley +1 more source
Small Cell Lung Cancer Associated With Cystic Airspace: A Case Report and Literature Review
We report a rare case of small cell lung cancer (SCLC) associated with a cystic airspace. Chest CT revealed a solid tumour component arising from the wall of a pre‐existing lung cyst. This case highlights the clinical importance of recognising cystic airspaces as potential sites for aggressive malignancies like SCLC.
Hiroyuki Shimada +7 more
wiley +1 more source
First microscopic and molecular parasitological survey of Strongylus vulgaris in Brazilian ponies. [PDF]
Martins AV +8 more
europepmc +1 more source

