Results 61 to 70 of about 2,458 (244)

Non‐canonical PKG1 regulation in cardiovascular health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Saint-Lo, Le Haras

open access: yes, 2017
74; Saint Lo, Le Haras, ND Phot ; Correspondence on the back in French. Addressed to: Monsieur Le Crissy, Chateau Se Feugire.

core  

De la collecte des ovocytes à la production d’embryons

open access: yesINRAE Productions Animales, 1999
Cet article fait partie du dossier Actualités en reproduction ...
J. BÉZARD
doaj   +1 more source

Peripheral targets for neuropathic pain

open access: yesBritish Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour   +3 more
wiley   +1 more source

Prevalência de anemia infecciosa equina em haras de Minas Gerais [PDF]

open access: yes, 2011
Dissertação (mestrado)—Universidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, 2011.A equideocultura está em constante expansão e a Anemia Infecciosa Equina (AIE) é um obstáculo ao seu desenvolvimento por ser uma doença transmissível e ...
Fiorillo, Karina Silva
core  

Développement folliculaire terminal : évolution biochimique du follicule

open access: yesINRAE Productions Animales, 1999
Cet article fait partie du dossier Actualités en reproduction ...
N. GÉRARD
doaj   +1 more source

Aktywność turystyczna argentyńskiej Polonii na przykładzie mieszkańców Buenos Aires – w świetle badań pilotażowych

open access: yesPrace Komisji Geografii Przemysłu Polskiego Towarzystwa Geograficznego, 2020
Głównym celem badań jest określenie aktywności turystycznej argentyńskiej Polonii na przykładzie mieszkańców Buenos Aires. W 2017 i 2018 roku przeprowadzone zostały pilotażowe badania ankietowe, dzięki którym uzyskana została informacja dotycząca ...
Kamila Ziółkowska-Weiss   +1 more
doaj   +1 more source

Afatinib Overcomes Osimertinib Resistance via Egfr V804F Mutation in a Syngeneic Egfr‐Mutant Lung Cancer Mouse Model

open access: yesCancer Science, EarlyView.
Using an immunocompetent mouse model of Egfr Ex19del‐driven lung cancer, we found that osimertinib‐resistant tumors acquired Egfr V804F, the murine counterpart of human EGFR V802F. Afatinib, but not osimertinib, suppressed phosphorylation of EGFR and overcame V804F‐mediated resistance, providing a preclinical rationale for biomarker‐guided therapy ...
Takaaki Tanaka   +22 more
wiley   +1 more source

Amniotic fluid is important for the maintenance of maternal responsiveness and the establishment of maternal selectivity in sheep

open access: yesAnimal, 2010
Amniotic fluid (AF) is important for the establishment of maternal behaviour in inexperienced ewes, but its role in experienced mothers remains to be studied. Here, the maintenance of post-partum maternal responsiveness and the establishment of exclusive
P. Poindron   +6 more
doaj   +1 more source

Elevated serum galectin‐3 levels predict the incidence of type 2 diabetes mellitus in a Japanese general population: A 10‐year follow‐up study

open access: yesJournal of Diabetes Investigation, EarlyView.
Elevated serum galectin‐3 levels are associated with the incidence of T2DM independent of insulin resistance, particularly among non‐obese individuals. There may be a diabetogenic mechanism that is not mediated by obesity or insulin resistance. ABSTRACT Aims/Introduction Although several studies have reported elevated serum galectin‐3 levels in type 2 ...
Harumi Takubo‐Yoshimura   +8 more
wiley   +1 more source

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