Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Temperature and Prey Availability Drive Seasonal Variations in Diet, Abundance and Condition of <i>Forsterygion lapillum</i> Across Two Coastal Habitats. [PDF]
Ecol EvolResende AC, Vinagre C, Rogers A.
europepmc +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Editorial Note: Investigating water movements around a shallow shipwreck in Big Tub Harbour of Lake Huron: Implications for managing and preserving underwater shipwrecks. [PDF]
PLoS OnePLOS One Editors.
europepmc +1 more source
2.06.006 Much Music, Tickle Harbour With Paddy Keenan
, 1997 Clip from Much Music about traditional music in Newfoundland. They are back stage at the Paddy Keenan concert at Holy Heart of Mary auditorium, interviewing Kelly Russell and Don ...
MuchMusic (Firm);
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Estimating historic seabed carbon disturbance by port dredging and aggregate extraction in NW Europe. [PDF]
PLoS OneMaynard E +6 more
europepmc +1 more source
Sydney Harbour Bridge, [ca. 1932, 6] [picture]
, 1932 Part of collection: Album of photographs of the Sydney Harbour Bridge during construction.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic ...
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Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Comment on Rivas et al. Unexpectedly Low Rate of Metastasis and Death Among Patients Treated for Uveal Melanoma with Brachytherapy, Vitrectomy, and Silicone Oil. <i>Cancers</i> 2025, <i>17</i>, 2683. [PDF]
Cancers (Basel)Correa ZM +7 more
europepmc +1 more source