Results 41 to 50 of about 68,235 (259)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Two-Hour Sea Level Oscillations in Halifax Harbour
Journal of Marine Science and EngineeringHalifax Harbour, a major seaport in Nova Scotia that is approximately 100 km southeast of the Bay of Fundy, comprises a deep inner region called Bedford Basin, connected to the adjacent ocean by a shallow channel called The Narrows.
Dan Kelley +6 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
ACROSSThe end of the 19th century found the Danube navigation in a full process of diversification of river operators, who fiercely disputed their economic interest, among them, the Hungarian company Magyar Folyam és Tengerhajózási Részvénytársaság – MFTR ...
Ionel Constantin MITEA
doaj +2 more sources
Immunotherapy-related gastritis: Two case reports and literature review
Clinical Medicine Insights: Oncology, 2021 Immunotherapy is increasingly defining a role in a wide variety of tumours such that as use becomes more ubiquitous, so too will the complications. A relatively rare complication of immunotherapy use is immune-related gastritis.
Rachel Woodford +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Water circulation forecasting in Spanish harbours
Scientia Marina, 2012 This paper describes the first harbour circulation forecasting system implemented in Spain. The configuration design was based on previous analyses of the morphologic and hydrodynamic behaviour of three harbours: Barcelona, Tarragona and Bilbao. A nested
Manel Grifoll +6 more
doaj +1 more source
International Journal of Applied Mechanics and Engineering, 2020 Hydrodynamic forces on a submerged cylinder in uniform finite depth ice-covered water is formulated by using the method of multipoles, the ice-cover being modelled as an elastic plate of very small thickness.
M. Sahu, D. Das
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