Results 91 to 100 of about 197,269 (235)

Seals at sea: modelling seal distribution in the German bight based on aerial survey data [PDF]

, 2009
The Wadden Sea is an important habitat for harbour seals and grey seals. They regularly haul-out on sandbanks and islands along the coast. Comparably little is known about the time seals spend at sea and how they use the remainder of the North Sea.
Scheidat, M., Herr, H., Siebert, U., Lehnert, K.   +3 more
core   +1 more source

Degrading GPX4 via Biomimetic Nanoparticle‐Mediated In Situ Synthesis of Deep‐Learning‐Designed Binder‐Degron Chimeras for Prostate Cancer Therapy

Advanced Science, EarlyView.
A deep‐learning‐designed binder is fused to a combinatorial degron to create a binder‐degron chimera (bdC) that recruits the CUL2‐RING ubiquitin ligase complex. Encapsulation in a prostate‐cancer‐targeted, CD47‐camouflaged nanocarrier enables tumor‐specific in situ bdC expression, triggering GPX4 degradation and ferroptosis, thereby establishing a ...
Si‐Han Zhang, Ye An, Na Zeng, Mei‐Cheng Liu, Jian‐Xuan Sun, Xi Gong, Jin‐Zhou Xu, Shao‐Gang Wang, Qi‐Dong Xia   +8 more
wiley   +1 more source

Harbour seals in the North Atlantic and the Baltic

NAMMCO Scientific Publications, 2010
Preface to Volume 8: Harbour seals in the North Atlantic and the ...
Mario Acquarone
doaj   +1 more source

A Scalable Droplet Microfluidic Platform That Overcomes Large‐Cell Constraints for Long‐Term Plant Cell Culture and Embryogenesis Analysis

Advanced Science, EarlyView.
This work presents a large‐cell‐compatible droplet microfluidic platform that overcomes long‐standing barriers in plant cell culture by enabling high‐fidelity encapsulation, novel multilayer 3D droplet incubation for scalable long‐term culture, and support for the full developmental progression of large plant cells.
Arman Mirmiran, Fangchi Shao, Gregory Datto, Tathansh Joshi, Elizabeth Chatt, Yashar Bashirzadeh, Dan Stessman, Lai Wei, Kuangwen Hsieh, Hena Guo, Tza‐Huei Wang   +10 more
wiley   +1 more source

Epizootics in harbour seals (Phoca vitulina): clinical aspects

NAMMCO Scientific Publications, 2010
Epizootic diseases causing considerable mortality in harbour seal populations have mainly been reported from the waters of the United States and Europe. Such die-offs were largely attributable to viral infections.
Ursula Siebert, Frances Gulland, Timm Harder, Thierry Jauniaux, Henrike Seibel, Peter Wohlsein, Wolfgang Baumgärtner   +6 more
doaj   +1 more source

MN•CS•IO System: Cross‐Species Study for HBB Function in High‐Altitude Hypoxia Adaptation

Advanced Science, EarlyView.
We developed an integrative mesh‐nanorod sorting, chitosan nanoparticle delivery, and intraosseous injection (MN•CS•IO) system to investigate HBB in high‐altitude hypoxia adaptation. Transplanting Tibetan animals' HBB‐modified Lin‐ cells into mice achieved 95.59% transfection efficiency and 8.15% HBB expression. High‐altitude HBB recipients upregulated
Wenqiao Hui, Lin Mao, Binggang Li, Hanyue Kang, Zhengquan Tang, Sheng Chen, Hui Yang, Yu Qiao, Huiqian Ding, Yuhuan Wang, Min Li, Junjie Hu, Shoudong Ye, Xin Wang, Xiaobin Xu, Yupeng Wang, Tana Wuren, Qian Ban, Baowei Zhang   +18 more
wiley   +1 more source

Aversiveness of sound in marine mammals : psycho-physiological basis, behavioural correlates and potential applications [PDF]

, 2010
Understanding what psycho-physiological and behavioural factors influence aversiveness of sound in marine mammals is important for conservation and practical applications.
Götz, Thomas
core   +2 more sources

Harbour porpoises (Phocoena phocoena) and wind farms: a case study in the Dutch North Sea [PDF]

, 2011
The rapid increase in development of offshore wind energy in European waters has raised concern for the possible environmental impacts of wind farms. We studied whether harbour porpoise occurrence has been affected by the presence of the Dutch offshore ...
Scheidat, M., Teilmann, J., Brasseur, S.M.J.M., Reijnders, P.J.H., Carstensen, J., van Polanen Petel, T., Polanen Petel, T., van, Tougaard, J.   +7 more
core   +1 more source

Status of harbour seals (Phoca vitulina) in the Baltic proper

NAMMCO Scientific Publications, 2010
The small population of harbour seals in the Baltic proper descend from seals that entered into the Baltic some 8,000 years ago. They form a genetically separate population with private alleles not present elsewhere.
Tero Härkönen, Erik Isakson
doaj   +1 more source

Neonatal Sevoflurane Exposure Induces Long‐Term Cognitive Impairment via Epigenetically Mediated MMP9 Activation and Perineuronal Net Disruption in the Hippocampal CA2

Advanced Science, EarlyView.
Hippocampal CA2 perineuronal nets ensheathing excitatory pyramidal neurons are selectively vulnerable to repeated neonatal sevoflurane exposure. Epigenetic upregulation of MMP9 via reduced H3K27me3 disrupts PNN integrity, impairs BDNF–TrkB signaling, and causes synaptic protein loss and dendritic spine deficits, leading to persistent social and spatial
Lirong Liang, Jiachen Wang, Taozhi Wang, Yanling Li, Youyi Zhao, Guanghui Hao, Peiqin Gong, Ruling Chen, Yilin Fang, Shengxi Wu, Haopeng Zhang, Hui Zhang   +11 more
wiley   +1 more source