Results 121 to 130 of about 55,916 (268)
Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes
This review synthesizes advances in bone organoid engineering and evaluates their potential to model diabetic bone fragility. Current in vitro and animal models do not fully recapitulate diabetes‐associated skeletal phenotypes. Cell‐based and scaffold‐based bone organoids are discussed as complementary approaches to reconstruct multicellular bone ...
Shuangzhe Lin +2 more
wiley +1 more source
Citizen science informs human-tick exposure in the Northeastern United States
Background Tick-borne disease is the result of spillover of pathogens into the human population. Traditionally, literature has focused on characterization of tick-borne disease pathogens and ticks in their sylvatic cycles.
W. Tanner Porter +7 more
doaj +1 more source
We developed a macrophage‐based therapeutic platform, termed trackable tolerogenic macrophages (TTM), for dual‐function immunomodulation and visualization in vivo. TTM cells were engineered to overexpress PD‐L1, incorporate bioorthogonal cell surface tags, and load rapamycin for sustained release.
Yihui Wang +14 more
wiley +1 more source
The Dynamical Evolution of Stellar Black Holes in Globular Clusters
Our current understanding of the stellar initial mass function and massive star evolution suggests that young globular clusters may have formed hundreds to thousands of stellar-mass black holes, the remnants of stars with initial masses from $\sim 20 ...
Morscher, Meagan +4 more
core +1 more source
Microbial synthesis of nanomaterials (NMs) is eco‐friendly, but the screening of microorganisms is limited by inefficient traditional methods (currently only involving∽400 microorganisms/90 NMs). We propose AI framework MicrobeDiscover, integrating a knowledge graph of microbe‐NM interactions.
Ludi Wang +12 more
wiley +1 more source
“More” Artificial mRNAs: Beyond the Art of Nature
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui +3 more
wiley +1 more source
Protocol for encapsulating ticks to study tick hematophagy and tick-virus-host interactions
Summary: Hard ticks can acquire and transmit various pathogens during their multi-day blood feeding events. Here, we present a protocol for encapsulating ticks while they feed on mice. We describe steps for affixing tick capsules to mice, counting ticks,
Eliane Esteves +3 more
doaj +1 more source
First detection of tacheng tick virus 2 in hard ticks from southeastern kazakhstan
We aim to detect the presence of Tacheng tick virus 2 (TcTV-2) in ticks of southeastern Kazakhstan. A total of 205 ticks were collected and separated into four species, namely Hyalomma scupense, Dermacentor marginatus, Hyalomma asiaticum and Hyalomma anatolicum.
Yuqing JIA +7 more
openaire +1 more source
Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi +4 more
wiley +1 more source
Background: West Azerbaijan is considered as a main region for domestic animal breeding. Due to importance of herd as a main host and ticks as a vector of relapsing fever and CCHF, a comprehensive study was undertaken in the region.
Sh Salari Lak +4 more
doaj

