Results 121 to 130 of about 55,916 (268)

Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes

open access: yesAdvanced Science, EarlyView.
This review synthesizes advances in bone organoid engineering and evaluates their potential to model diabetic bone fragility. Current in vitro and animal models do not fully recapitulate diabetes‐associated skeletal phenotypes. Cell‐based and scaffold‐based bone organoids are discussed as complementary approaches to reconstruct multicellular bone ...
Shuangzhe Lin   +2 more
wiley   +1 more source

Citizen science informs human-tick exposure in the Northeastern United States

open access: yesInternational Journal of Health Geographics, 2019
Background Tick-borne disease is the result of spillover of pathogens into the human population. Traditionally, literature has focused on characterization of tick-borne disease pathogens and ticks in their sylvatic cycles.
W. Tanner Porter   +7 more
doaj   +1 more source

Trackable Tolerogenic Macrophages Integrate PD‐L1 and Rapamycin Signaling to Suppress Alloimmune Responses in Transplantation

open access: yesAdvanced Science, EarlyView.
We developed a macrophage‐based therapeutic platform, termed trackable tolerogenic macrophages (TTM), for dual‐function immunomodulation and visualization in vivo. TTM cells were engineered to overexpress PD‐L1, incorporate bioorthogonal cell surface tags, and load rapamycin for sustained release.
Yihui Wang   +14 more
wiley   +1 more source

The Dynamical Evolution of Stellar Black Holes in Globular Clusters

open access: yes, 2014
Our current understanding of the stellar initial mass function and massive star evolution suggests that young globular clusters may have formed hundreds to thousands of stellar-mass black holes, the remnants of stars with initial masses from $\sim 20 ...
Morscher, Meagan   +4 more
core   +1 more source

MicrobeDiscover: A Knowledge Graph–Enabled AI Framework for Identifying Microbes for Inorganic Nanomaterial Biosynthesis

open access: yesAdvanced Science, EarlyView.
Microbial synthesis of nanomaterials (NMs) is eco‐friendly, but the screening of microorganisms is limited by inefficient traditional methods (currently only involving∽400 microorganisms/90 NMs). We propose AI framework MicrobeDiscover, integrating a knowledge graph of microbe‐NM interactions.
Ludi Wang   +12 more
wiley   +1 more source

“More” Artificial mRNAs: Beyond the Art of Nature

open access: yesAdvanced Science, EarlyView.
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui   +3 more
wiley   +1 more source

Protocol for encapsulating ticks to study tick hematophagy and tick-virus-host interactions

open access: yesSTAR Protocols
Summary: Hard ticks can acquire and transmit various pathogens during their multi-day blood feeding events. Here, we present a protocol for encapsulating ticks while they feed on mice. We describe steps for affixing tick capsules to mice, counting ticks,
Eliane Esteves   +3 more
doaj   +1 more source

First detection of tacheng tick virus 2 in hard ticks from southeastern kazakhstan

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2021
We aim to detect the presence of Tacheng tick virus 2 (TcTV-2) in ticks of southeastern Kazakhstan. A total of 205 ticks were collected and separated into four species, namely Hyalomma scupense, Dermacentor marginatus, Hyalomma asiaticum and Hyalomma anatolicum.
Yuqing JIA   +7 more
openaire   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

open access: yesAdvanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi   +4 more
wiley   +1 more source

Seasonal Activity of Ticks and their Importance in Tick-Borne Infectious Diseases in West Azerbaijan, Iran

open access: yesJournal of Arthropod-Borne Diseases, 2008
Background: West Azerbaijan is considered as a main region for domestic animal breeding. Due to importance of herd as a main host and ticks as a vector of relapsing fever and CCHF, a comprehensive study was undertaken in the region.
Sh Salari Lak   +4 more
doaj  

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