Results 51 to 60 of about 9,582 (270)

Two kinds of ferritin protect ixodid ticks from iron overload and consequent oxidative stress.

open access: yesPLoS ONE, 2014
Ticks are obligate hematophagous parasites that have successfully developed counteractive means against their hosts' immune and hemostatic mechanisms, but their ability to cope with potentially toxic molecules in the blood remains unclear.
Remil Linggatong Galay   +9 more
doaj   +1 more source

MORPHOLOGCAL AND MOLECULAR STUDY OF HARD TICKS SPECIES THAT INFESTED SMALL RUMINANTS IN DUHOK GOVERNORATE, KURDISTAN REGION, IRAQ [PDF]

open access: yesBasrah Journal of Veterinary Research, 2020
Ticks are harmful ectoparasite that feed on human and animal blood and causing manydiseases through the world. They infested many hosts including: mammals, reptiles and birds.Ticks are important vector and they have the ability to transmit a variety of ...
Shameeran Salman Ismael   +1 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Anaplasma spp. identification in hard ticks of Iran: First report of Anaplasma bovis in Haemaphysalis inermis

open access: yes, 2016
International audienceThe aim of the present study was to determine the presence of Anaplasma spp. in hard ticks in the north of Iran. Tick samples were collected from sheep and goats grazing in Savadkooh, Mazandaran province and identified under a ...
Shayan, P.   +3 more
core   +1 more source

FIGURE 1 in Molecular identification of common hard ticks (Acari: Ixodidae) in Xinjiang, China

open access: yes, 2021
FIGURE 1. Phylogenetic tree of 8 common species of hard ticks in Xinjiang based on the CO1 gene with the neighbor-joining method (bootstrap replicates: 1000).Published as part of Wang, Qiguo, Zhang, Yujiang, Sun, Surong, Luo, Tao, Mou, Wenting, Li, Bo ...
Luo, Tao   +9 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Biological and ecological characteristics of soft ticks (Ixodida: Argasidae) and their impact for predicting tick and associated disease distribution

open access: yesParasite, 2009
As evidence of global changes is accumulating, scientists are challenged to detect distribution changes of vectors, reservoirs and pathogens caused by anthropogenic and/or environmental changes.
Vial L.
doaj   +1 more source

Borreliae Part 2: Borrelia Relapsing Fever Group and Unclassified Borrelia

open access: yesBiology, 2021
Borreliae of the relapsing fever group (RFG) are heterogenous and can be divided mainly into three groups according to vectors, namely the soft-tick-borne relapsing fever (STBRF) Borreliae, the hard-tick-borne relapsing fever (HTBRF) Borreliae, the louse-
Giusto Trevisan   +6 more
doaj   +1 more source

An Immunosuppressant Peptide from the Hard Tick Amblyomma variegatum [PDF]

open access: yesToxins, 2016
Ixodid ticks are well known for spreading transmitted tick-borne pathogens while being attached to their hosts for almost 1–2 weeks to obtain blood meals. Thus, they must secrete many immunosuppressant factors to combat the hosts’ immune system. In the present work, we investigated an immunosuppressant peptide of the hard tick Amblyomma variegatum ...
Yufeng Tian   +6 more
openaire   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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