Results 81 to 90 of about 45,289 (325)

Linking Sensitive Data: Methods and Techniques for Practical Privacy-Preserving Information Sharing

International Journal of Population Data Science, 2021
Springer, November 2020 ISBN-10: 3030597059, ISBN‑13: 978-3030597054, Price: £87.50 Key message from the preface A key message of this book is that any database that contains sensitive information about individuals in plaintext can be vulnerable to
Peter Christen, Thilina Ranbaduge, Rainer Schnell   +2 more
doaj  

Validation of Soft Classification Models using Partial Class Memberships: An Extended Concept of Sensitivity & Co. applied to the Grading of Astrocytoma Tissues

, 2013
We use partial class memberships in soft classification to model uncertain labelling and mixtures of classes. Partial class memberships are not restricted to predictions, but may also occur in reference labels (ground truth, gold standard diagnosis) for ...
Beleites, Claudia, Salzer, Reiner, Sergo, Valter   +2 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Modèle de compaction élasto-plastique en simulation de bassins Elastoplastic Compaction Model for Basin Simulation

Oil & Gas Science and Technology, 2006
Cet article présente un modèle de compaction des sédiments pour simulateurs de bassins sédimentaires. Dans ce modèle, les concepts précédemment utilisés dans le modèle TEMISPACK sont généralisés et décrits en s'inspirant des formalismes propres à la ...
Schneider F.
doaj   +1 more source

Magnitude of beam-hardening artifacts produced by gutta-percha and metal posts on cone-beam computed tomography with varying tube current [PDF]

, 2020
Hugo Gaêta‐Araujo, Eduarda Helena Leandro Nascimento, Rocharles Cavalcante Fontenele, Arthur Xavier Maseti Mancini, Deborah Queiroz Freitas, Christiano Oliveira‐Santos   +5 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Key features of numerical models for the FE-simulation of deep tunnel advance by the NATM

Underground Space
In the present work, important aspects of time-dependent nonlinear 3D finite element (FE) models for deep tunnel advance by the New Austrian Tunneling Method (NATM), characterized by repeated sequences of excavation, securing, and idle periods, are ...
Peter Gamnitzer, Matthias Neuner, Magdalena Schreter-Fleischhacker, Alexander Dummer, Thomas Mader, Stefan Smaniotto, Günter Hofstetter   +6 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Bayesian parameter identification in plasticity [PDF]

, 2017
To evaluate the cyclic behaviour under different loading conditions using the kinematic and isotropic hardening theory of steel a Chaboche visco-plastic material model is employed.
Adeli, Ehsan, Matthies, Hermann G., Reinstädler, Sven, Rosic, Bojana   +3 more
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source