Results 21 to 30 of about 316,511 (219)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Extending Reflectometry Range: A Zero-Crossing Algorithm for Thick Film Metrology

Metrology
Accurate and high-efficiency film metrology remains a key challenge in High-Volume Manufacturing (HVM), where conventional spectroscopic reflectometry and white light interferometry (WLI) are either limited by model dependence or throughput. In this work,
Zimu Zhou, Enrique A. Lopez-Guerra, Iulica Zana, Vu Nguyen, Nguyen Quoc Huy Tran, Violet Huang, Bojun Zhou, Gary Qian, Michael Kwan, Peter Wilkens, Chester Chien   +10 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A Survey on Split Manufacturing: Attacks, Defenses, and Challenges

IEEE Access, 2020
In today's integrated circuit (IC) ecosystem, owning a foundry is not economically viable, and therefore most IC design houses are now working under a fabless business model.
Tiago D. Perez, Samuel Pagliarini
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Simulated and measured piezoelectric energy harvesting of dynamic load in tires

Heliyon
From 2007 in US and from 2022 in EU it is mandatory to use TPMS monitoring in new cars. Sensors mounted in tires require a continuous power supply, which currently only is from batteries.
Henrik Staaf, Simon Matsson, Sobhan Sepheri, Elof Köhler, Kaies Daoud, Fredrik Ahrentorp, Christian Jonasson, Peter Folkow, Leena Ryynänen, Mika Penttila, Cristina Rusu   +10 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

28 Nanometers FPGAs Support for High Throughput and Low Power Cryptographic Applications

Journal of Advances in Information Technology, 2013
The current unprecedented advancements of communication systems and high performance computing urged for a high throughput applications with power consumption within a predefined budget.
Yaser Jararweh, Lo'ai Tawalbeh, Hala Tawalbeh, Abidalrahman Moh’d   +3 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Book review of Evaluating literacy instruction: Principles and promising practices.

Canadian Journal for New Scholars in Education, 2019
This review provides a description, assessment and critique for Gabriel & Allington’s edited book, Evaluating Literacy Instruction: Principles and Promising Practices.
Shawnee Hardware
doaj