Results 131 to 140 of about 440,485 (323)

PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou   +14 more
wiley   +1 more source

Fractional Schrodinger-Poisson systems with weighted Hardy potential and critical exponent

open access: yesElectronic Journal of Differential Equations, 2020
In this article we consider the fractional Schrodinger-Poisson system $$\displaylines{ (-\Delta)^{s} u - \mu \frac{\Phi(x/|x|)}{|x|^{2s}} u +\lambda \phi u = |u|^{2^*_s-2}u,\quad \text{in } \mathbb{R}^3,\cr (-\Delta)^t \phi = u^2, \quad \text{in ...
Yu Su   +3 more
doaj  

Improving Genotype Imputation in High‐Dimensional Pharmacogenomics Using Multiple Imputation: Evaluation with Machine Learning Approaches

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Multiple imputation is well‐established for handling missing data, yet its use in high‐dimensional genetic datasets remains limited. Using pharmacokinetic tuberculosis simulations and SNP data (1000 Genomes Project), we compared machine learning (ML) and traditional approaches (e.g., mean imputation and complete‐case analysis) for imputation and ...
Innocent G. Asiimwe   +6 more
wiley   +1 more source

Bound state solutions for quasilinear Schrödinger equations with Hardy potential

open access: yesResults in Applied Mathematics
This paper is concerned with the existence of bound state solutions for quasilinear Schrödinger equations with Hardy potential and Berestycki–Lions type conditions.
Yanfang Xue, Wenjing Gu, Jianxin Han
doaj   +1 more source

Sustainable Development, Environmental Certification and the Financial Performance of the Road Passenger Transportation Sector

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Within the framework of sustainable development and environmental policy, environmental certification is regarded as a mechanism through which road passenger transport companies (RPTCs) could mitigate their adverse environmental impacts and attain competitive advantages that may enhance their financial performance.
Jose Antonio Cavero‐Rubio   +1 more
wiley   +1 more source

Realigned Hardy’s paradox

open access: yesResults in Physics
Hardy’s paradox provides an “All-versus-Nothing” fashion to directly certify that quantum mechanics cannot be completely described by local realistic theory. However, when considering potential imperfections in experiments, like noisy entanglement source
Shuai Zhao   +9 more
doaj   +1 more source

An assessment of stress and production rate of sucker rod heat pipes in oil well pumping system

open access: yesDeep Underground Science and Engineering, EarlyView.
The sucker rod pumping system is the preferred oil extraction technique. The concept about equipping the hollow vacuum space in solid sucker rods with heat pipe has been scrutinized in terms of stress and oil production evaluation. Abstract The implementation of the heat pipe concept in sucker rods for oil pumping systems negates the requirement for an
R. S. Anand   +5 more
wiley   +1 more source

Surface hydration‐induced damage in tight oil‐bearing sandy conglomerate reservoirs

open access: yesDeep Underground Science and Engineering, EarlyView.
A series of techniques such as X‐ray diffraction, scanning electron microscopy, energy‐dispersive spectroscopy, conductivity tests, and infrared thermal imaging were used. The key findings are the identification of a two‐stage surface hydration process and the elucidation of the effects of various minerals and elements on the hydration process ...
Anbang Zhao   +5 more
wiley   +1 more source

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