Results 171 to 180 of about 13,639 (251)

The pharmacology of gepants in migraine: A scoping review on mechanisms, clinical applications, and combination strategies

open access: yesHeadache: The Journal of Head and Face Pain, Volume 66, Issue 7, Page 1628-1643, July/August 2026.
Abstract Background Calcitonin gene‐related peptide (CGRP) is a key mediator in migraine pathophysiology, and the development of gepants, novel CGRP receptor antagonists, has expanded therapeutic options for both acute and preventive treatment. This scoping review aims to synthesize current evidence on the pharmacology, clinical applications, safety ...
Luigi Francesco Iannone   +5 more
wiley   +1 more source

The Efficacy of Intracanal Medicaments Within the Regenerative Endodontic Procedures on Permanent Necrotic Immature Teeth: Systematic Review and Naïve Indirect‐Comparison Meta‐Analysis

open access: yesInternational Endodontic Journal, Volume 59, Issue 7, Page 1337-1357, July 2026.
ABSTRACT Objectives The objectives of this study were to estimate and compare the 1‐year clinical success rates of triple antibiotic paste (TAP), double antibiotic paste (DAP), calcium hydroxide (CH) within regenerative endodontic procedures (REPs) on permanent necrotic immature teeth.
Mario Alovisi   +2 more
wiley   +1 more source

Women's social care provision in prison has improved but challenges remain: findings from a national survey in England eight years after the 2014 Care Act. [PDF]

open access: yesBMC Public Health
Buck D   +10 more
europepmc   +1 more source

Limited Plasticity of Stomatal Development in Apple Trees Across Diverse European Climates

open access: yesPhysiologia Plantarum, Volume 178, Issue 4, July/August 2026.
ABSTRACT Climate change affects plant acclimation and adaptation, particularly in long‐lived perennial crops like apple (Malus domestica Borkh.). Stomata play an essential role in regulating these plant environmental responses. This study examined variation in stomatal density (SD) and stomatal function of apple trees in 2022–2023 across four European ...
Francesca Zuffa   +12 more
wiley   +1 more source

Narrative systematic review for autism spectrum disorders screening tools in school settings. [PDF]

open access: yesBMJ Open
McCann LJ   +10 more
europepmc   +1 more source

V̇O2max$\dot V_{\rm{O_{2max}}}$‐based all‐out aerobic exercise attenuates hexosamine biosynthetic pathway activity: Metabolomic insights in mice model

open access: yesExperimental Physiology, Volume 111, Issue 7, Page 3253-3266, 1 July 2026.
Abstract Aerobic exercise enhances physiological performance by activating metabolic systems, including glucose oxidation and fat metabolism. Cellular glucose predominantly flows through glycolysis (95–98%), whereas a smaller fraction (2–5%) enters the hexosamine biosynthetic pathway (HBP), generating UDP‐N‐acetylglucosamine.
Gyumin Kang   +3 more
wiley   +1 more source

Descending inhibitory rostral ventromedial medulla neurons cause widespread antinociception and contribute to the pain-inhibits-pain phenomenon. [PDF]

open access: yesNat Commun
Ganley RP   +14 more
europepmc   +1 more source

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