Results 191 to 200 of about 909,127 (312)

Suicidal Behaviour, Self-Harm and Related Factors: A Retrospective Study from the Adolescent Psychiatric Unit. [PDF]

Children (Basel)
Lesinskienė S, Zabarauskaitė M, Valiulis T, Dailidė G, Germanavičius A.   +4 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Psychological and cognitive-emotional moderators of suicidal ideation and self-harm in young adults. [PDF]

Sci Rep
Dickhoff J, Deng W, Aleman A, de Vries V, Opmeer EM, van Tol MJ.   +5 more
europepmc   +1 more source

Harm reduction or harm maintenance? [PDF]

Nicotine & Tobacco Research, 2002
openaire   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Clinical guidelines on self-harm and suicide prevention: taking uncertainty into account in the evidence base. [PDF]

BMJ Ment Health
Seyedsalehi A, Fazel S.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Leveraging mHealth interventions to reduce sex- and drug-related risk behaviors among chemsex-involved men who have sex with men: evidence from a qualitative study. [PDF]

Harm Reduct J
Gautam K, Uyar C, Wickersham JA, Paudel K, Azwa I, Altice FL, Sujan MSH, Ha T, Copenhaver MM, Shrestha R.   +9 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Sexual Violence, Posttraumatic Stress, and Heterosexism in Relation to Suicide and Self-Harm Risk in Bisexual + College Students. [PDF]

Arch Suicide Res
Salim SR, Kaysen DL, Mazzone GM, Ellis JR, Gilmore AK.   +4 more
europepmc   +1 more source