Results 31 to 40 of about 691,976 (317)

Physiological and transcriptome analysis reveals the differences in nitrate content between lamina and midrib of flue-cured tobacco

Scientific Reports, 2022
Nitrate is an important precursor of tobacco-specific nitrosamines (TSNAs) and a remarkable difference in nitrate accumulation between lamina and midrib of flue-cured tobacco has long been observed.
Yuqing Feng, Yuanyuan Zhao, Yafei Li, Jun Zhou, Yujing Li, Hongzhi Shi   +5 more
doaj   +1 more source

Harm reduction among injecting drug users - evidence of effectiveness

, 2010
This chapter synthesises and evaluates the available direct evidence relating to the impact of needle and syringe programmes (NSPs), opioid substitution treatment (OST), drug consumption rooms (DCRs), and peer naloxone distribution (PND) on HIV/hepatitis
Rhodes, T., Kerr, Thomas, Palmateer, N., Goldberg, David J., Hedrich, Dagmar, Palmateer, Norah, Fry, Craig L, Goldberg, David, Palmateer, Norah; id_orcid, Rhodes, Tim, Goldberg, D.J., Stöver, H., Hickman, Matthew, Hutchinson, Sharon, Hall, Wayne, Hickman, M., Brentari, C., Kimber, J., Kimber, Jo, Fischer, Benedikt, Hutchinson, S.J., Stevens, Alex, Dubois-Arber, Françoise, Hutchinson, Sharon J.; id_orcid   +23 more
core   +1 more source

Alcohol-related mortality following self-harm: a multicentre cohort study.

, 2014
OBJECTIVES: To assess alcohol-related premature death in people who self-harm compared to the general population, including variation by socioeconomic deprivation.
Waters, K, Steeg, Sarah; id_orcid, Haigh, Matthew, Kapur, Navneet; id_orcid, Webb, Roger, Steeg, Sarah, Kapur, Nav, Ness, Jennifer, Hawton, Keith, Haigh, M, Bergen, H, Hawton, K, Steeg, S, Bergen, Helen, Ness, J, Webb, R, Kapur, N, Cooper, Jayne, Waters, Keith, Cooper, J   +19 more
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Do No Harm [PDF]

AMA Journal of Ethics, 2018
After a goals-of-care conversation, this patient's chart listed his status as "full-code." As shown in this image, resuscitation was initiated for a 92-year-old man with metastatic malignancy after being found pulseless by the rounding team.
openaire   +2 more sources

High-dose naloxone formulations are not as essential as we thought

Harm Reduction Journal
Naloxone is an effective FDA-approved opioid antagonist for reversing opioid overdoses. Naloxone is available to the public and can be administered through intramuscular (IM), intravenous (IV), and intranasal spray (IN) routes.
Paige M. Lemen, Daniel P. Garrett, Erin Thompson, Megan Aho, Christina Vasquez, Ju Nyeong Park   +5 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Sustainability of opioid agonist therapy programmes in Belarus, the Republic of Moldova, Tajikistan and Ukraine in the context of transition from Global Fund support during 2020–2023

Harm Reduction Journal
Background Most national programmes of opioid agonist therapy (OAT) in Eastern Europe and Central Asia are at a critical juncture for building their sustainability due to decreasing support from the Global Fund and other international HIV funders ...
Raminta Stuikyte, Ivan Varentsov, Naimdzhon Malikov, Sergii Dvoriak, Myroslava Filippovych, Alisher Latypov, Aleksei Kralko, Ala Iatco, Catherine Cook   +8 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Managing xylazine-involved overdoses in a community harm reduction setting: lessons from Tijuana, Mexico

Harm Reduction Journal
Background Xylazine is a α2-adrenergic receptor agonist, used for sedation in veterinary contexts. Although it is increasingly found in overdose deaths across North America, the clinical management of xylazine-involved overdoses has not been extensively ...
Lilia Pacheco Bufanda, Alejando González Montoya, Brenda Torres Carrillo, Mariana Alejandra Gonzalez Tejeda, Luis A. Segovia, Alhelí Calderón-Villarreal, Joseph R. Friedman   +6 more
doaj   +1 more source