Results 161 to 170 of about 4,746,761 (313)

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Swedish snus for tobacco harm reduction [PDF]

, 2007
Mats Lambe
openalex   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

50 years of harm reduction in Europe: high time for transformation. [PDF]

Harm Reduct J
Jeziorska I, Martinelli TF, Kools JP.
europepmc   +1 more source

A qualitative assessment of stakeholder perceptions and socio-cultural influences on the acceptability of harm reduction programs in Tijuana, Mexico [PDF]

, 2008
Morgan M. Philbin, Remedios Lozada, María Luisa Zúñiga, Andrea Mantsios, Patricia Case, Carlos Magis‐Rodríguez, Carl A. Latkin, Steffanie A. Strathdee   +7 more
openalex   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Colonial harm in new packaging: Indigenous critiques of the tobacco industry's 'harm reduction' rhetoric. [PDF]

Health Promot Int
Maddox R, Heris C, Waa A, Teddy L, Upton P, Henderson PN, Kornacki C, Rodriguez J, Lee J, Tautolo ES, Martinez SA, Bradbrook SK, Kennedy M.   +12 more
europepmc   +1 more source

Preventing HIV transmission among Iranian prisoners: Initial support for providing education on the benefits of harm reduction practices [PDF]

, 2008
Babak Eshrati, Rahim Taghizadeh Asl, Colleen Anne Dell, Parviz Afshar, Peggy MargaretE Millson, Mohammad Kamali, John R. Weekes   +6 more
openalex   +1 more source

Harm reduction [PDF]

Bulletin des Médecins Suisses, 2019
openaire   +2 more sources

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source