Cancer‐associated fibroblasts (CAFs) play different roles in NSCLC progression and metastasis. Their heterogeneous origins and phenotypes shape the tumor microenvironment and influence metastatic spread. This review highlights NSCLC CAF subtypes, their potential cellular sources, and their differential distribution across primary tumors and distant ...
Alejandro Bernardo+3 more
wiley +1 more source
Rural providers' attitudes toward integrating harm reduction strategies and PrEP prescribing into rural primary care settings in the US. Southeast and Midwest. [PDF]
Marotta PL+14 more
europepmc +1 more source
Substantial reduction of inappropriate tablet splitting with computerised decision support: a prospective intervention study assessing potential benefit and harm [PDF]
Renate Quinzler+4 more
openalex +1 more source
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura+7 more
wiley +1 more source
The peers expanding engagement in stimulant harm reduction with contingency management study: a protocol paper. [PDF]
Cooke A+11 more
europepmc +1 more source
Harm reduction for injecting opiate users: an update and implications in China [PDF]
Maja Meise+6 more
openalex +1 more source
Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma+10 more
wiley +1 more source
EXPANDED ACCESS TO SEPs AND OTHER HARM REDUCTION MEASURES IN FRANCE [PDF]
Patrizia Carrieri+1 more
openalex +1 more source
Key role for inhibins in effective T cell activation, migration and Th17 differentiation
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco+5 more
wiley +1 more source
Mini-review: Harm reduction strategies among people who intentionally use fentanyl. [PDF]
Paredes J+3 more
europepmc +1 more source