Results 301 to 310 of about 5,563,712 (386)

The role of stigma in impeding implementation of harm reduction services in San Francisco. [PDF]

SSM Qual Res Health
Akiba CF, Megerian CE, Chung EO, Morris T, Wenger LD, Suen LW, Lambdin BH, Kral AH.   +7 more
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Colonial harm in new packaging: Indigenous critiques of the tobacco industry's 'harm reduction' rhetoric. [PDF]

Health Promot Int
Maddox R, Heris C, Waa A, Teddy L, Upton P, Henderson PN, Kornacki C, Rodriguez J, Lee J, Tautolo ES, Martinez SA, Bradbrook SK, Kennedy M.   +12 more
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Social justice with harm reduction approaches for mothers who use opioids: an international comparative ethnographic study with community engaged methods. [PDF]

Harm Reduct J
Boeri MW, Lamonica A, Whittaker A, Bruce M.   +3 more
europepmc   +1 more source

Harm reduction measures in a recreational gym user with anabolic androgenic steroid dependence: a case report in the context of current best clinical practice

Magnolini, Raphael, Bottoni, Sofia Laura, Hammer, Helena, Capraro, Joël, Bruggmann, Philip, Senn, Oliver   +5 more
openalex   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Developing and testing a digital harm reduction app for GBMSM engaging in chemsex: a feasibility study grounded in users' lived experiences. [PDF]

Harm Reduct J
Strong C, Joson PA, Huang P, Chen CC, Li CW, Tseng YC, Chuang TT, Wu HJ, Ku SW.   +8 more
europepmc   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Welfare first: transforming harm reduction at UK festivals. [PDF]

Harm Reduct J
Janes J.
europepmc   +1 more source