Results 61 to 70 of about 15,469,363 (346)
Climate change and global health: A call to more research and more action
Allergy. European Journal of Allergy and Clinical Immunology, 2022 There is increasing understanding, globally, that climate change and increased pollution will have a profound and mostly harmful effect on human health.
I. Agache +31 more
semanticscholar +1 more source
Implications of and possible responses to climate change [PDF]
, 2009 Climate change is expected to worsen food insecurity and seriously undermines rural development prospects. It makes it harder to achieve the Millenium Development Goals and ensure a sustainable future beyond 2015.
Kahiluoto, Helena, Rötter, Reimund
core
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Control of Power Electronics Converters and Electric Motor Drives
Energies, 2021 With the increased emphasis on climate change and reducing harmful emissions in the atmosphere, interest in power electronics converters and electric motor drives has led to significant new developments in areas such as renewable energy systems or ...
Federico Barrero, Jorge Rodas
doaj +1 more source
Controlled drinking, harm reduction and their roles in the response to alcohol-related problems [PDF]
, 2006 This article first distinguishes three meanings of the term ‘harm reduction’ in the literature on alcohol problems: a European sense in which a change in drinking is not necessarily required; an American sense which includes the controlled drinking (CD ...
Heather, Nick
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Importance of Dark Septate Endophytes in Agriculture in the Face of Climate Change
Journal of FungiClimate change is a notable challenge for agriculture as it affects crop productivity and yield. Increases in droughts, salinity, and soil degradation are some of the major consequences of climate change.
Victoria Huertas +4 more
doaj +1 more source
Community conversations as a strategy to change harmful traditional practices against women
, 2017 This article conducts a series of list experiments to detect whether community conversations contribute to a change in thinking about harmful traditional practices in Ethiopia.
E. D. Cao +3 more
semanticscholar +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source