Results 71 to 80 of about 15,469,363 (346)

Hurricanes, El Niño and harmful algal blooms in two sub-tropical Florida estuaries: Direct and indirect impacts

Scientific Reports, 2020
Future increases in the intensity of hurricanes and El Niño periods predicted by climate change models have focused attention on their role in stimulating harmful algal blooms (HABs). A series of hurricanes that recently impacted Florida (USA) provided a
E. Phlips, S. Badylak, N. Nelson, K. Havens   +3 more
semanticscholar   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Changing contexts of harm

, 2022
Carlene Firmin, Michelle Lefevre, Nathalie Huegler, Delphine Peace   +3 more
  +4 more sources

“Do no harm”: Fortifying MDT collaboration in changing technological times [PDF]

International Journal of Medical Informatics, 2013
To examine the changes in multidisciplinary medical team activity and practices, with respect to the amount of patient cases, the information needs and technology used, with up to 10 multidisciplinary teams (MDTs) in a large teaching hospital over a 10-year period.An investigation of MDT meeting activity was undertaken in November 2005 and repeated in ...
KANE, BRIDGET THERESA, LUZ, SATURNINO
openaire   +4 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Transforming the economic landscape for global sustainability

Ecology and Society
The economic system’s interdependent relationship with nature is fraught with contradictions. While over half of global GDP moderately or highly depends on nature and subsidies to sectors driving nature’s decline, e.g., agriculture, fossil fuels ...
Victoria Reyes-García, Ram Pandit, Karina Benessaiah, Arun Agrawal, Lucas A. Garibaldi, Chinwe Ifejika Speranza, Karen O'Brien, Timothée Parrique, Sebastian Villasante   +8 more
doaj   +1 more source

Community voices: Achieving real diversity in STEM requires the ability to transform institutions

Nature Communications, 2022
Resilience is often invoked to address systemic marginalization (e.g. racism) in academia but inadvertently maintains harmful systems. We argue that the ability to transform systems, as opposed to persevering within them, must be prioritized to make real,
Jory C. Lerback, Monique M. Holt, Gabriela A. Enriquez St. Pierre, Annie Putman, Crystal L. Tulley-Cordova, William A. Smith, Liliana Caughman, Stephanie Alvarez   +7 more
doaj   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Influence of Key Strata on the Gas Downward Leakage Law in Dual-System of Coal Seam

Geofluids, 2020
In Datong mining area, CO and other harmful gases were discharged from the gob in the Jurassic overburden strata to the panel of Carboniferous coal seam.
Feng Du, Kun Jiao, Zhanyuan Ma
doaj   +1 more source