Results 221 to 230 of about 1,011,636 (279)

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee   +9 more
wiley   +1 more source

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

open access: yesAdvanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater   +13 more
wiley   +1 more source

Differential geometry-based harmonic analysis of three-phase systems. [PDF]

open access: yesSci Rep
Sundriyal N   +4 more
europepmc   +1 more source

Unconventional high-harmonic generation in resonant membrane metasurfaces. [PDF]

open access: yesNat Commun
Tonkaev P   +7 more
europepmc   +1 more source

Unraveling the Relevant Length and Time Scales of Elastomers in a High Strain Rate Test. [PDF]

open access: yesMacromolecules
Evans KM   +4 more
europepmc   +1 more source

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