Results 51 to 60 of about 22,339,861 (301)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Influence of the Supply Voltage Variation on the Conducted Emission in the Frequency Range up to 150 kHz Injected into the Power Grid by CFL and LED Lamps—Case Study

Applied Sciences
In normal operating conditions, the mains voltage level provided by low-voltage distribution networks follows time-varying patterns within permissible limits.
Wojciech Frydlewicz, Łukasz Michalec, Paweł Kostyła, Dominika Kaczorowska, Tomasz Sikorski   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A classification of the harmonic frames up to unitary equivalence

, 2011
Up to unitary equivalence, there are a finite number of tight frames of n vectors for Cd which can be obtained as the orbit of a single vector under the unitary action of an abelian group G (for nonabelian groups there may be uncountably many).
Waldron, Shayne, Chien, T-Y
core   +1 more source

Fractional Fourier transforms, harmonic oscillator propagators and Strichartz estimates on Pilipovic and modulation spaces [PDF]

, 2023
We show that harmonic oscillator propagators and fractional Fourier transforms are essentially the same. We deduce continuity properties and fix time estimates for such operators on modulation spaces, and apply the results to prove Strichartz estimates ...
Manna, Ramesh, Ramesh Manna, Bhimani, Divyang G., Bhimani, Divyang, Joachim Toft, Divyang G. Bhimani, Toft, Joachim   +6 more
core   +1 more source

Identifying harmonic attributes from online partial discharge data [PDF]

, 2011
Partial discharge (PD) monitoring is a key method of tracking fault progression and degradation of insulation systems. Recent research discovered that the harmonic regime experienced by the plant also affects the PD pattern, questioning the conclusions ...
Rowland, S.M., Bahadoorsingh, S., Mcarthur, Stephen, Catterson, Victoria, Rudd, Susan   +4 more
core   +4 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

On X ̃-frames and conjugate systems in Banach spaces

Sahand Communications in Mathematical Analysis, 2014
The generalization of p-frame in Banach spaces is considered in this paper. The concepts of an X~-frame and a system conjugate to X~-frame were introduced. Analogues of the results on the existence of conjugate system were obtained.
Migdad Ismailov, Afet Jabrailova
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source