Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Detection of Inter-turn Faults in Five-Phase Permanent Magnet Synchronous Motors
Five-phase permanent magnet synchronous motors (PMSMs) have inherent fault-tolerant capabilities. This paper analyzes the detection of inter-turn short circuit faults in five-phase PMSMs in their early stage, i.e. with only one turn in short circuit by
SAAVEDRA, H., RIBA, J.-R., ROMERAL, L.
doaj +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
The Influence of Measurement Methodology on the Accuracy of Electrical Waveform Distortion Analysis
The present paper covers a review of documents that specify measurement methods of voltage waveform distortion. It also presents measurement stages of waveform components that are uncommon in the classic fundamentals of electrotechnics and signal theory,
Bartman Jacek, Kwiatkowski Bogdan
doaj +1 more source
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
Current Controller with FOPI Modification for VSI-based Active Power Filter
The integration of photovoltaic (PV) systems into the grid, combined with nonlinear loads and bidirectional power flows, significantly impacts grid voltage stability and total harmonic distortion (THD) in low-voltage distribution systems.
Antonius Doddy Tyas Prasetyo +2 more
doaj +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Harmonic Analysis of a Nonstationary Series of Temperature Paleoreconstruction for the Central Part of Greenland [PDF]
The results of the investigations of a transformed series of reconstructed air temperature data for the central part of Greenland with an increment of 30 years have been presented.
T.E. Danova, B.V. Perelygin
doaj
Operator Theory and Harmonic Analysis
D. Albrecht, X. Duong, A. Mcintosh
semanticscholar +1 more source
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source

