Results 71 to 80 of about 205,537 (300)
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Goals and Strategies for Open Fan Design
International Journal of Turbomachinery, Propulsion and PowerThis paper highlights recent activities associated with the design of an uninstalled open fan propulsor for next-generation civil aircraft in the high-subsonic flight regime.
Carola Rovira Sala +4 more
doaj +1 more source
Abstract and Applied Analysis, 2014 This paper develops a theoretical analysis of harmonic balance method, based on the cubic spline wavelet and Daubechies wavelet, for steady state analysis of nonlinear circuits under periodic excitation.
Jing Gao
doaj +1 more source
C-Band Resistive SiC-MESFET mixer [PDF]
, 2002 In this paper the design and characterization of a linear C-band single ended resistive SiC-MESFET mixer is presented. The mixer has a minimum conversion loss of 7.8 dB and has a third order intermodulation intercept point of 30.3 dBm.
Andersson, Kristoffer +3 more
core +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
A programmable frequency scan algorithm based on harmonic balance
iEnergyThis paper presents a programmable frequency scan algorithm based on harmonic balance. The core idea involves treating systems under perturbation as nonlinear time-periodic (NTP) systems.
Lu Miao +6 more
doaj +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
The accuracy of the Generalized-α method in the time integration of non-linear Single- and Two-DOF forced systems [PDF]
, 2006 International audienceThis paper deals with the accuracy of a numerical time integration scheme, the implicit Generalized- α method, when applied near resonant conditions in periodic steady-state vibrations of elastic linear and nonlinear systems.
Baldo, Gabriele +3 more
core +4 more sources
Power quality enhancement using power balance theory based DSTATCOM [PDF]
, 2016 The DSTATCOM (Distributed Static Compensator) is used for current harmonic mitigation, Power Factor Correction (PFC), reactive power compensation, load balancing and neutral current compensation in the Power Distribution System (PDS).
Bangarraju, Jampala +2 more
core +2 more sources
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source