Results 51 to 60 of about 188,454 (278)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Influence of Parameters on the Excitation Power of Third Harmonic Brushless Hybrid Excitation Generator

open access: yesEnergies
Hybrid-excited generators have a wide voltage regulation capability or a wide range of variable-speed constant-voltage output capability, providing a significant advantage in the new energy power generation field.
Yonghong Xia   +5 more
doaj   +1 more source

Second Harmonic Coherent Driving of a Spin Qubit in a Si/SiGe Quantum Dot

open access: yes, 2015
We demonstrate coherent driving of a single electron spin using second harmonic excitation in a Si/SiGe quantum dot. Our estimates suggest that the anharmonic dot confining potential combined with a gradient in the transverse magnetic field dominates the
Coppersmith, S. N.   +8 more
core   +1 more source

Excited Sessile Drops Dance Harmonically

open access: yes, 2013
In our fluid dynamics video, we demonstrate our method of visualizing and identifying various mode shapes of mechanically oscillated sessile drops. By placing metal mesh under an oscillating drop and projecting light from below, the drop's shape is visualized by the visually deformed mesh pattern seen in the top view.
Chang, Chun-Ti   +2 more
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Parity forbidden excitations of Sr2CuO2Cl2 revealed by optical third-harmonic spectroscopy

open access: yes, 2001
We present the first study of nonlinear optical third harmonic generation in the strongly correlated charge-transfer insulator Sr2CuO2Cl2. For fundamental excitation in the near-infrared, the THG spectrum reveals a strongly resonant response for photon ...
A. B. Schumacher   +26 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Collective Excitations, Nambu-Goldstone Modes and Instability of Inhomogeneous Polariton Condensates

open access: yes, 2011
We study non-equilibrium microcavity-polariton condensates (MPCs) in a harmonic potential trap theoretically. We calculate and analyze the steady state, collective-excitation modes and instability of MPCs.
A. M. J. Schakel   +8 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Analysis and Design of a Brushless WRSM with Harmonic Excitation Based on Electromagnetic Induction Power Transfer Optimization

open access: yesMagnetism
This paper proposes a method to analyze the effect of the rotor’s harmonic winding design and the output of a brushless wound rotor synchronous machine (WRSM) for optimal excitation power transfer.
Arsalan Arif   +6 more
doaj   +1 more source

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