Results 181 to 190 of about 493,296 (323)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

Remote‐Controllable Immune‐Priming Spot Formation Via Nanocomplexed Hydrogel‐Assisted Histotripsy: Immunoasis

open access: yesAdvanced Materials, EarlyView.
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim   +9 more
wiley   +1 more source

Managing the power supply energy efficiency by means of higher harmonics [PDF]

open access: diamond
Gennadiy Pivnyak   +7 more
openalex   +1 more source

Ubiquitous Antiparallel Domains in 2D Hexagonal Boron Nitride Uncovered by Interferometric Nonlinear Optical Imaging

open access: yesAdvanced Materials, EarlyView.
Interferometric second‐harmonic generation (SHG) imaging reveals the ubiquitous formation of antiparallel domains in CVD‐grown 2D hexagonal boron nitride. By resolving lattice orientation and SHG phase, hidden domain structures and disorder become visible over large areas. The SHG intensity quantitatively tracks crystalline quality across growth routes,
Yeri Lee   +12 more
wiley   +1 more source

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