Results 51 to 60 of about 5,313 (212)

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

A COMPARATIVE STUDY BETWEEN HARMONIC SCALPEL HEMOSTASIS AND CONVENTIONAL HEMOSTASIS IN TOTAL AND SUBTOTAL THYROIDECTOMY [PDF]

Basrah Journal of Surgery, 2017
A COMPARATIVE STUDY BETWEEN HARMONIC SCALPEL HEMOSTASIS AND CONVENTIONAL HEMOSTASIS IN TOTAL AND SUBTOTAL THYROIDECTOMY Mohammed Salim Mohammed*, Jasim D Saud#, Mansour Amin Mohammed$ & Mazin H Al-Hawaz@ *MB,ChB, Board Candidate.
Mohammed Salim Mohammed, Jasim D Saud, Mansour Amin Mohammed, Mazin H Al-Hawaz   +3 more
doaj   +1 more source

SLPI⁺ AT2‐Like Cells Orchestrate Lung Adenocarcinoma Invasion via Wnt Pathway Activation and Stromal Crosstalk in a Spatially Defined Margin Niche

Advanced Science, EarlyView.
Integrating spatial transcriptomics and single‐cell RNA sequencing, this study identifies a novel subpopulation of SLPI⁺ AT2‐like cells at the invasive margin of lung adenocarcinoma (LUAD). These cells, through stromal crosstalk and Wnt pathway activation, promote tumor stemness and invasion.
Zhoufeng Wang, Guonian Zhu, Pan Tang, Yan Wang, Wenxin Luo, Wenpeng Song, Zhikang Pan, Bingjie Zheng, YongChao Jiang, Defu Xiao, Xin Jin, Yong Bai, Guowei Che, Weimin Li   +13 more
wiley   +1 more source

Multimodal Layer‐Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes

Advanced Science, EarlyView.
The study introduces a flexible microfluidic axialtrode that integrates optical, electrical, and chemical modalities within a single polymer fiber. By redistributing electrodes and fluidic channels along the fiber axis via angled cleaving, it enables simultaneous optogenetic stimulation, electrophysiological recording, and drug delivery across brain ...
Kunyang Sui, Neela K. Codadu, Daman Rathore, Guanghui Li, Marcello Meneghetti, Anders L. Bøcker, Rune W. Berg, Rob C. Wykes, Christos Markos   +8 more
wiley   +1 more source

Innovations in microsurgery: The role of non‐invasive blood perfusion imaging—A review and framework

Clinical Advances in Periodontics, EarlyView.
Abstract Background This review evaluates current literature on non‐invasive blood perfusion imaging in periodontology, with a focus on applications in periodontal microsurgery. Methods A hypothesis‐building review was conducted by two reviewers from January 2022 to April 2025 across multiple databases. Results Laser speckle contrast imaging (LSCI) and
Amanda B. Rodriguez, Oliver D. Kripfgans, Diego Velasquez, Hsun‐Liang Chan   +3 more
wiley   +1 more source

Preliminary results of postoperative pain and complications after hemorrhoidectomy with harmonic scalpel [PDF]

Einstein (São Paulo), 2006
Objective: To assess pain and to describe the complications afterhemorrhoidectomy (Milligan-Morgan technique) using theharmonic scalpel. Methods: The sample was composed of 108patients.
Nelson de Souza Liboni, José Humberto Tavares Guerreiro Fregnani   +1 more
doaj  

The first experience of the simultaneous application of ultrasound scalpel and laser in the treatment of hemorrhoids.

Medičnì Perspektivi, 2018
In recent decades in Ukraine, there has been a steady increase in the incidence of hemorrhoids among the working people, which makes it an important socio-economic problem.
P. F. Gulmamedov, A. P. Kondratenko
doaj   +1 more source

Structural characterization of newt tendon regeneration after complete transection: In vivo two‐photon imaging and transmission electron microscopy

Journal of Anatomy, EarlyView.
The present study characterized newt digital flexor tendon regeneration structurally at both micro‐ and nanoscales following complete transection and suggested that the mechanism of tissue regeneration differs between the early phase (until 6 weeks) and the late phase (after 6 weeks). Tendon stubs remained separated for up to 2 weeks after transection,
Tomoka Kamiya, Yusaku Ito, Tomohito Iwasaki, Daisuke Suzuki, Toshinori Hayashi, Jeonghyun Kim, Takeo Matsumoto, Eijiro Maeda   +7 more
wiley   +1 more source

Periodontal and orthodontic management of impacted canines

Periodontology 2000, EarlyView.
Abstract The maxillary and mandibular canines are described by many clinicians as the “cornerstone” of the arch. When in their optimal position, they play a critical role in providing a well‐balanced occlusal scheme that contributes toward functional as well as neuromuscular stability, harmony, esthetics, and dentofacial balance.
Mohammad Qali, Chenshuang Li, Chun‐Hsi Chung, Nipul Tanna   +3 more
wiley   +1 more source

THE HARMONIC SCALPEL APPLICATION IN THYROID SURGERY [PDF]

Journal of IMAB, 2013
New, modern devices for tissue resection have been introduced in the surgical treatment of thyroid diseases recent years.Aim: To present our experience with the use of the harmonic scalpel in thyroid surgery.Patients and methods: For the period 2008 ...
Rumen Nenkov, Radoslav Radev, Ekaterina Marinova, Nikolay Cvetkov, Anatoli Semkov, Borislav Petrov   +5 more
doaj   +1 more source