Results 211 to 220 of about 93,145 (342)
PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu +11 more
wiley +1 more source
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang +9 more
wiley +1 more source
Intensity Noise Suppression in Photonic Detector Systems for Spectroscopic Applications. [PDF]
Wu Y, Ma K, Wu Z, Zhang W.
europepmc +1 more source
Cochannel speaker separation by harmonic enhancement and suppression
D.P. Morgan +3 more
openalex +2 more sources
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Harmonic-Recycling Passive RF Energy Harvester with Integrated Power Management. [PDF]
Li R, Hu Y, Li H, Jin H, Liao D.
europepmc +1 more source
Dilute but Dense – Reversible Crosslinking Enables Water‐Rich (Bio)polymer Condensates
Reversible crosslinking between two types of (bio)polymers drives liquid–liquid phase separation even in good solvent. The arrangement of binding motifs controls condensate formation and density, and internal network structure. Simulations and theory reveal a closed‐loop coexistence phase diagram at very low monomer concentrations and re‐entrant ...
Xinxiang Chen +4 more
wiley +1 more source
WUSCHEL Transcription Factor: From Stem Cell Maintenance to Crop Improvement
This review synthesizes emerging insights into WUSCHEL (WUS) as a central regulator of plant stem cell fate beyond Arabidopsis, highlighting its roles in regeneration, somatic embryogenesis (SE), and stress adaptation across crops. It explores how WUS‐centered regulatory networks, genome editing, and AI‐guided strategies can be leveraged for precise ...
Zishan Ahmad +6 more
wiley +1 more source

