Results 121 to 130 of about 28,532 (263)

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

open access: yesAdvanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing   +10 more
wiley   +1 more source

Noninvasive Characterization of Tumor Heterogeneity in HNSCC: From Clinical Utility to Biological Correlates

open access: yesAdvanced Science, EarlyView.
This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen   +15 more
wiley   +1 more source

Utility of Harmonisation for Fixel-Based Metrics in Travelling Subjects and Alzheimer's Disease Data. [PDF]

open access: yesHum Brain Mapp
Zou R   +13 more
europepmc   +1 more source

Topology‐Aware Deep Learning on Higher‐Order Structures for Drug Response Prediction

open access: yesAdvanced Science, EarlyView.
We present TopDr, a topology‐aware deep learning framework that encodes both drugs and cell lines as multiscale simplicial complexes, capturing interactions at the 0‐, 1‐, and 2‐simplex levels. By jointly integrating local higher‐order neighborhoods and global topological structures, TopDr generates enriched representations for sensitivity prediction ...
Cong Shen   +3 more
wiley   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

open access: yesAdvanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du   +11 more
wiley   +1 more source

Efficient Direct Recycling of Spent Batteries: Integrated Lithiation and Delamination

open access: yesAdvanced Science, EarlyView.
An integrated process for the delamination and relithiation of spent cathodes, LixNi0.6Co0.2Mn0.2O2 and LixFePO4, under open‐air conditions is proposed. The transition‐metal (Ni) oxidation state in the cathode is reduced by the oxidation of diethylene glycol, facilitating relithiation. Glycol aldehyde formation induces 100% electrode delamination.
Jeonghwan Song   +11 more
wiley   +1 more source

Dynamic Evolution‐Controlled Parabolic‐Shaped Microstructures for Ultra‐Black Surface via Self‐Assembled Microsphere Mask Etching

open access: yesAdvanced Science, EarlyView.
A robust, substrate‐independent fabrication approach overcomes the spectral and geometric limitations of traditional stray‐light suppression. By combining ink spray‐coating with self‐assembled microsphere mask etching, this method produces parabolic‐shaped microstructures on diverse planar and curved engineering components.
Yiming Li   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy