Results 161 to 170 of about 324,522 (341)

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li   +22 more
wiley   +1 more source

Commodity tax competition and industry location under the destination- and the origin-principle [PDF]

open access: yes
We develop a model of commodity tax competition with monopolistically competitive internationally mobile firms, transport costs, and asymmetric country sizes.
BEHRENS, Kristian   +3 more
core  

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

open access: yesAdvanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu   +13 more
wiley   +1 more source

The performance of the supply chain: Strategical harmonization [PDF]

open access: yes
On this paperwork, we define the strategy of the logistic chain and we explain the way in which the creation of a strategical harmonization between the competitive strategy of the companz and the strategz of the logistic chain affects the performance of ...
Oana Seitan
core  

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

open access: yesAdvanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu   +9 more
wiley   +1 more source

AKUNTANSI INTERNASIONAL : HARMONISASI VERSUS STANDARDISASI

open access: yesJurnal Akuntansi dan Keuangan, 1999
Legal, social, and economic environment and conditions which differ among countries influence accounting standards which, consequently, differ among countries.
Arja Sadjiarto
doaj  

Does Indirect Tax Harmonization Deliver Pareto Improvements in the Presence of Global Public Goods? [PDF]

open access: yes
This paper identifies conditions under which, starting from any tax distorting equilibrium, destination- and origin-based indirect tax-harmonizing reforms are potentially Pareto improving in the presence of global public goods.
Christos Kotsogiannis   +2 more
core  

CPIExtract: A software package to collect and harmonize small molecule and protein interactions [PDF]

open access: gold
Andrea Piras   +4 more
openalex   +1 more source

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