Results 151 to 160 of about 1,239,317 (297)

Social harmony at work: A sharedness index linking team atmosphere to individual well-being in a Japanese company. [PDF]

PLoS One
Ito K, Wakamiya S, Manabe M, Watanabe Y, Nakayama M, Uchida Y, Aramaki E.   +6 more
europepmc   +1 more source

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

Advanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo, Tianlong Luo, Lingfeng Li, Qi Sun, Dongquan Li, Shanhe Huang, Zonglin Li, Weilong Lin, Yuan Ou, Tao Du, Shengmeng Peng, Kewei Xu, Bisheng Cheng, Hai Huang   +13 more
wiley   +1 more source

Assessment and Characterization of Induced Alloantigen-Specific Regulatory T Cells Obtained by the Inhibition of CDK8/19 with the AS2863619 Compound. [PDF]

Int J Mol Sci
Bulygin A, Fisher M, Kurilin V, Alrhmoun S, Perik-Zavodskii R, Perik-Zavodskaia O, Volynets M, Shkaruba N, Obleukhova I, Khantakova J, Golikova E, Silkov A, Sennikov S.   +12 more
europepmc   +1 more source

Grain Boundary‐Driven Lattice Dynamics in a Solid‐State Li‐Ion Conductor

Advanced Science, EarlyView.
Grain boundaries in Li3OCl${\rm Li}_3{\rm OCl}$ are shown to significantly alter its lattice dynamics and induce Li‐ion vibrational hardening and anion softening. These changes hinder ion transport while promoting electronic conductivity and instability.
Jack M. Hemingway, James A. Quirk, Erli Lu, James A. Dawson   +3 more
wiley   +1 more source

Genetics and environment distinctively shape the human immune cell epigenome. [PDF]

Nat Genet
Wang W, Hariharan M, Ding W, Bartlett A, Barragan C, Castanon R, Wang R, Rothenberg V, Song H, Nery JR, Aldridge A, Altshul J, Kenworthy M, Liu H, Tian W, Zhou J, Zeng Q, Chen H, Wei B, Gündüz IB, Norell T, Broderick TJ, McClain MT, Satterwhite LL, Burke TW, Petzold EA, Shen X, Woods CW, Fowler VG, Ruffin F, Panuwet P, Barr DB, Beare JL, Smith AK, Spurbeck RR, Vangeti S, Ramos I, Nudelman G, Sealfon SC, Castellino F, Walley AM, Evans T, Müller F, Greenleaf WJ, Ecker JR.   +44 more
europepmc   +1 more source

Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair

Advanced Science, EarlyView.
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li, Xin Xing, Beicheng Du, Myles Zhou, Austin Z. Chen, Mary Archer, Chunbao Rao, Manyu Zhu, Masnsen Cherief, Aaron W. James   +9 more
wiley   +1 more source

ECM remodeling features in reparative chondrocytes during knee osteoarthritis. [PDF]

Front Endocrinol (Lausanne)
Li F, Zhang Z, Peng J, Zhang H, Xiong Y, Zheng Z, Xu R, Ruan J, Yang Q, Lu Z, Ma X, Wang C, Dai B, Zhu J.   +13 more
europepmc   +1 more source

Data‐Driven Modeling of Composition–Processing–Microstructure Relations for Recycled Aluminum Cast Alloys

Advanced Science, EarlyView.
Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang, Waleed Mohammed, Dierk Raabe   +2 more
wiley   +1 more source

Implant Treatment After Traumatic Tooth Loss: A Retrospective Cohort Study of Survival, Esthetic, and Patient-Reported Outcome. [PDF]

Clin Exp Dent Res
Petersen FN, Dahl M, Hosseini M, Jensen SS.   +3 more
europepmc   +1 more source

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

Advanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu, Xin Chen, Qingyang Zhao, Weikang Tan, Lingrui Zhu, Kin Liao, Vincent Chan, Nicolae Goga, Winfred O. Larkotey, Yang Li, Yinghui Shi, Wenya Shu, Lin Wang, Weiqing Wang, Tian Jian Lu, Yulong Han   +15 more
wiley   +1 more source