Results 171 to 180 of about 2,882,429 (393)

The Politics of Framing the Student Problem: Inquiries Into Australian Civics Education, 2006–2024

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Recurring debates about civics, the kinds of history that should, and should not, be taught in school, and ‘standards debates’ about the ‘basics’ typically follow on the heels of recurring moral panics about the ‘declining’ state of ‘our’ education system.
Patrick O'Keeffe   +2 more
wiley   +1 more source

Olfactory Impairment and Incident Cognitive Decline: A Systematic Review and Meta‐Analysis

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory impairment (OI) is associated with poor ageing outcomes. While cross‐sectional studies found a high prevalence of OI among patients with neurodegenerative diseases, the temporal relationship remains unclear. This meta‐analysis aims to synthesise the longitudinal association of OI with cognitive decline (CD). Methods PubMed,
Brian Sheng Yep Yeo   +17 more
wiley   +1 more source

TARDBP (TDP‐43) Knock‐in Zebrafish Display a Late‐Onset Motor Phenotype and Loss of Large Spinal Cord Motor Neurons

open access: yesAnnals of Neurology, EarlyView.
Objective Mutations in TARDBP (encoding TDP‐43) are associated with the neurodegenerative disease amyotrophic lateral sclerosis (ALS) and include familial missense mutations where there are a lack of models and mechanisms examining how they are pathogenic.
Ziyaan A. Harji   +10 more
wiley   +1 more source

Mutations in the Key Autophagy Tethering Factor EPG5 Link Neurodevelopmental and Neurodegenerative Disorders Including Early‐Onset Parkinsonism

open access: yesAnnals of Neurology, EarlyView.
Objective Autophagy is a fundamental biological pathway with vital roles in intracellular homeostasis. During autophagy, defective cargoes including mitochondria are targeted to lysosomes for clearance and recycling. Recessive truncating variants in the autophagy gene EPG5 have been associated with Vici syndrome, a severe early‐onset neurodevelopmental
Hormos Salimi Dafsari   +140 more
wiley   +1 more source

Ultrasound‐Triggered Release of Anticancer Nanoparticles from Electrospun Fabrics Integrated with Soft Robotic Tentacles

open access: yesAdvanced NanoBiomed Research, EarlyView.
Early pancreatic cancer detection remains challenging, causing poor treatment outcomes. This article introduces an innovative, ultrasound (US)‐triggered localized drug delivery system using gelatin nanoparticles embedded in electrospun fabric and integrated with magnetic tentacle robotics.
Samuel C. T. Moorcroft   +6 more
wiley   +1 more source

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