Results 81 to 90 of about 267,949 (308)

Denial of Inpatient Genetic Testing: A Study on Outpatient Yield and Outcomes

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genetic conditions suspected in children often require genetic testing for accurate diagnoses, but testing remains costly. Case management teams review genetic test requests to improve access for patients while reducing the financial burden for medical institutions.
Cindy Y. Canales, Kathleen Shields, Meagan Choates, Paul Hillman, Laura Farach, Theresa Wittman, Kathryn Leal   +6 more
wiley   +1 more source

The Effects of High-Fidelity Simulation on Salivary Cortisol Levels in SRNA Students: A Pilot Study

The Scientific World Journal, 2011
The use of clinical simulation in graduate level nursing education provides the opportunity for students to learn and apply theoretical practices of nursing care in a safe and controlled environment.
Terri Jones, Sarah Goss, Bethany Weeks, Hiroko Miura, Damian Bassandeh, Dennis Cheek   +5 more
doaj   +1 more source

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

A Novel Gain‐of‐Function ITPR1 Variant Associated With a Movement Disorder Characterized by Tremor and Dystonia

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The 1,4,5‐trisphosphate receptor type 1 (ITPR1) gene encodes an endoplasmic reticulum calcium release channel, in which loss‐of‐function mutations have been associated with spinocerebellar ataxias and related neurological phenotypes. Only one gain‐of‐function mutation in the highly conserved suppressor domain of ITPR1 has been previously ...
Emilie T. Théberge, Bo Sun, Ruiwu Wang, Arezoo Mohajeri, Clara D. M. Van Karnebeek, Cornelius F. Boerkoel, Stephanie Huynh, Gabriella Horvath, S. R. Wayne Chen, Anna Lehman   +9 more
wiley   +1 more source

Directed Evolution of an Efficient Polycarbonate Depolymerase With Exceptional Operational Stability

Angewandte Chemie, EarlyView.
Here, we show that well studied PET hydrolases can be re‐engineered via directed evolution to deconstruct alternative aromatic‐containing commodity polymers. Introduction of only three mutations into LCCICCG was sufficient to generate an efficient polycarbonate hydrolase with high operational stability that can fully depolymerize a polycarbonate sample
Henry A. Jones, Amy E. Hutton, Dominic Harris‐Jukes, John Davidson, Linus O. Johannissen, Colin W. Levy, Michael P. Shaver, Anthony P. Green   +7 more
wiley   +2 more sources

Trauma‐Informed Practice in Welfare‐to‐Work and Employment Services: A Scoping Review

Australian Journal of Social Issues, EarlyView.
ABSTRACT There is increasing recognition within welfare services, including employment services, that many participants may have histories of trauma. Research suggests that experiences of trauma not only impact individuals' psychosocial health but also vocational elements such as job performance, employability, career progression, and financial ...
Emily Corbett, Michael McGann, Mark Considine, René Rejón   +3 more
wiley   +1 more source

Mechanism‐Guided Precision Hydrolysis of Early Transition Metals to Access (Mixed‐Metal) Oxo Clusters

Angewandte Chemie, EarlyView.
Precision hydrolysis enables the rational, room‐temperature synthesis of Zr and Hf oxo clusters with improved atom economy, sustainable solvents, and gram‐scale yields. By adding exactly 1.33 equivalents of water, Zr6, Hf6, and elusive bimetallic clusters are accessed, alongside new group 5 oxo clusters, providing a versatile and economical platform ...
Muhammed Jibin Parammal, Jikson Pulparayil Mathew, Alessandro Prescimone, Ajmal Roshan Unniram Parambil, Harry Wilson, Jonathan De Roo   +5 more
wiley   +2 more sources

Don't Worry About Her; Intersectionality, and the Role of Systems and Structures in the Embodied Experiences of Young Women's Use of Violence

Australian Journal of Social Issues, EarlyView.
ABSTRACT Systems and structures designed to protect and support young people, specifically (in this paper) young women, are ironically the same systems that maintain gender disparity. Consequently, this has influenced the embodied identities of young women who experience and use violence. Such systemic and structural intersectionality has impacted upon
Louise Rak, Tamara Blakemore, Elsie Randall, Meaghan Katrak Harris   +3 more
wiley   +1 more source

Navigating Nitration Chemistry: A Practical Guide to Reagents, Mechanisms, and Selectivity

Angewandte Chemie, EarlyView.
This review highlights key contributions of modern nitration chemistry, emphasizing sustainable mechanistic platforms and comparing the performance of both organic and inorganic reagents across aromatic, ipso‐, olefin, alkyne, and heteroatom nitration. It provides the community with a clearer, unified perspective on current advances and facilitates the
Harry Lecomte, Anthony J. Fernandes, Dmitry Katayev   +2 more
wiley   +2 more sources

Adventures in prehospital video laryngoscopy

Journal of the American College of Emergency Physicians Open, 2023
Slate Uys, Chris Conn, Cody Parrott, Jordan Anderson, Xavier Delarosa, Casey B. Patrick   +5 more
doaj   +1 more source