Results 171 to 180 of about 116,218 (224)

The cytotoxicity of gomesin peptides is mediated by the glycosphingolipid pathway and lipid-cholesterol interactions. [PDF]

open access: yesCell Death Discov
Fernandez-Carrasco I   +24 more
europepmc   +1 more source

Human FASTK preferentially binds single‐stranded and G‐rich RNA

open access: yesThe FEBS Journal, Volume 293, Issue 3, Page 729-748, February 2026.
Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak   +7 more
wiley   +1 more source

The importin‐alpha superfamily engages in ethylene signaling by shuttling ETHYLENE INSENSITIVE 2 from the endoplasmic reticulum to the nucleus

open access: yesThe FEBS Journal, Volume 293, Issue 3, Page 894-917, February 2026.
The plant hormone ethylene regulates plant growth, ripening, senescence, and stress responses. The hormonal signal transmission, from receptors at the ER membrane to the transcriptional regulators in the nucleus, is still not completely understood.
Fabian Wynen   +7 more
wiley   +1 more source

Quantification of the cerebral pressure–flow relationship directional sensitivity: Reliability of shorter repeated squat–stand durations

open access: yesExperimental Physiology, Volume 111, Issue 2, Page 357-374, 1 February 2026.
Abstract The magnitude of changes in middle cerebral artery mean blood velocity (MCAv) is attenuated when mean arterial pressure (MAP) increases compared with when MAP decreases. This directional sensitivity has been characterized using a time‐corrected ratio calculated on MCAv and MAP changes induced by repeated squat–stands (RSS) at 0.05 and 0.10 Hz ...
Lawrence Labrecque   +6 more
wiley   +1 more source

Effect of moderate altitude and nocturnal oxygen therapy on cerebrovascular function in patients with COPD: A randomized, crossover trial at 2048 m

open access: yesExperimental Physiology, Volume 111, Issue 2, Page 527-538, 1 February 2026.
Abstract We investigated whether nocturnal oxygen therapy improves next‐day cerebrovascular function in lowlanders with chronic obstructive pulmonary disease (COPD) staying at moderate altitude. This randomized, placebo‐controlled single‐blind crossover trial was performed in moderate‐to‐severe COPD patients [forced expiratory volume in 1 s (FEV1 ...
Dominic Gilliand   +12 more
wiley   +1 more source

Safety and efficacy of bio-engineered, autologous dermo-epidermal skin grafts in adolescent and adult burn patients: 1-year results of a prospective, randomized, controlled, multicenter phase IIB clinical trial. [PDF]

open access: yesEClinicalMedicine
Meuli M   +15 more
europepmc   +1 more source

Thinking Outside the Rocks: Subsurface Water Storage, Topography, and Land Cover Are Key Modulators of Large‐Scale Riverine Dissolved Silicon Dynamics

open access: yesGeophysical Research Letters, Volume 53, Issue 2, 28 January 2026.
Abstract Riverine dissolved silicon (DSi) dynamics reflect integrated geologic, hydrologic, climatic, and ecological controls. We compiled annual DSi data for 337 rivers across four continents and trained interpretable machine‐learning models to predict concentrations and yields from 28 watershed variables.
Sidney A. Bush   +6 more
wiley   +1 more source

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