Results 101 to 110 of about 188,379 (279)
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Influence of human factor on the time of work stages of harvesters and crane-equipped forwarders
Journal of Forest Science, 2008 Harvester technologies represent the second most common logging system in the Czech Republic. The high productivity of this technology is very necessary to cover its acquisition and operational costs.
J. Dvořák, Z. Malkovský, J. Macků
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
AgricultureTo reduce harvest losses of a pepper harvester with a drum of elastic tooth type picking mechanism, this paper proposes an optimization method using AHP (Analytic Hierarchy Process) and RSM (Response Surface Methodology), thereby identifying the optimal ...
Bingpeng Wang +6 more
doaj +1 more source
Social-ecological soundscapes: examining aircraft-harvester-caribou conflict in Arctic Alaska [PDF]
, 2017 Thesis (M.S.) University of Alaska Fairbanks, 2017As human development expands across the Arctic, it is crucial to carefully assess the impacts to remote natural ecosystems and to indigenous communities that rely on wild resources for nutritional and ...
Stinchcomb, Taylor R.
core
Fast design space exploration of vibration-based energy harvesting wireless sensors
, 2013 An energy-harvester-powered wireless sensor node is a complicated system with many design parameters. To investigate the various trade-offs among these parameters, it is desirable to explore the multi-dimensional design space quickly. However, due to the
Al-Hashimi, Bashir +4 more
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Design and Testing of a Pneumatic Jujube Harvester
AgronomyJujubes have a beautiful taste, and high nutritional and economic value. The planting area of dwarf and densely planted jujubes is large and shows an increasing trend; however, the mechanization level and efficiency of fresh jujube harvesting are low ...
Huaming Hou +7 more
doaj +1 more source