Results 111 to 120 of about 188,379 (279)
Estimating Cotton Harvest Cost per Acre When Harvest Days are Stochastic [PDF]
The cotton harvesting industry is in the beginnings of its next technological advance, cotton harvesters that form cotton modules inside the machine then deposit them off the rows.
Farrell, Matthew, Ibendahl, Gregory A.
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
浙江大学学报. 农业与生命科学版, 2015 Sucrose accounts for about 90% of the total amount of sugar in China. However, the mechanization degree and working efficiency on planting, harvesting and sugaring of sugarcane in China is far lower than western countries, and especially the problem of ...
Hu Jinbing, Wu Jianfeng, Wang Jun
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Electromechanical Modelling of a Piezoelectric Stack Energy Harvester
Proceedings, 2018 In this paper, the behavior of a piezoelectric stack generator subject to a direct mechanical force, such as that experienced by pedestrian loads, is characterized and modelled.
Matthew Evans +5 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
, 2008 This paper reports on a study of the effect of the passage of multi-axle harvesting machines on the soil physical properties. In particular, it investigates the effect of the rear tyre of a combine harvester on the amount of soil compaction subsequent to
Ansorge, Dirk, Godwin, R. J.
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Calculating Cost Savings Per Acre When Harvest Days are Stochastic [PDF]
New cotton harvesters have been introduced that have higher performance rate as well as eliminate extra labor and accompanying equipment. The new machines build partial modules on board the harvester.
Farrell, Matthew, Ibendahl, Gregory A.
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source