Results 111 to 120 of about 15,333 (299)

Blockchain technology disruptions: Exploring accounting and auditing academics and practitioners' perception

open access: yesAccounting &Finance, EarlyView.
Abstract This study explores the practical impact of blockchain technology (BCT), which contrasts strongly with literature that has predominantly hypothesised BCT's potential to disrupt accounting practice. We interviewed 44 practitioners and academics with knowledge of BCT across 13 countries and industries.
Musbaudeen Titilope Oladejo   +3 more
wiley   +1 more source

Estimating thresholds for risk of cannabis use disorder using standard delta‐9‐tetrahydrocannabinol (THC) units

open access: yesAddiction, EarlyView.
Abstract Background and aims Lower risk guidelines for safer levels of cannabis use could help to reduce the health burden posed by cannabis use disorder (CUD). We aimed to estimate risk thresholds for CUD based on delta‐9‐tetrahydrocannabinol (THC) consumption using standard THC units (1 unit = 5 mg THC).
Rachel Lees Thorne   +9 more
wiley   +1 more source

Adolescent cannabis use and psychological distress from 2013 to 2023: A population‐based study in Ontario, Canada

open access: yesAddiction, EarlyView.
Abstract Background and aims Epidemiologic research suggests that adolescent cannabis use is associated with psychological distress (i.e. depression and anxiety symptoms); however, most studies have relied on 20th‐century data, when cannabis was significantly less potent than today.
André J. McDonald   +12 more
wiley   +1 more source

A Scoping Systematic Review of Cannabis Use in Endometriosis

open access: yesAustralian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Endometriosis, affecting 6%–10% of reproductive‐age women, causes chronic pelvic pain, dysmenorrhea, and infertility. Current treatments have limitations and consequently there is rising interest in effects of cannabis on pain and inflammation associated with endometriosis.
Kindha McLaren   +2 more
wiley   +1 more source

Single Cell Analysis Reveals Dynamic Changes of Distinct Cell Populations in Human Nickel Allergy

open access: yesAllergy, EarlyView.
We investigated cell types mediating the early and late inflammatory responses in human Ni2+‐allergy by scRNA‐Seq. Early responsiveness was mainly mediated by TLR4+TAGLN− endothelial cells indirectly activating TLR4−KRT16+ keratinocytes, and CCR7+DCN+ DCs. Late responsiveness was crucially driven by infiltration of KLF2+ central memory T cells and TLR4+
Marc Schmidt   +7 more
wiley   +1 more source

Prolonged IL‐33 Exposure Switches the Secreted Mast Cell Cytokine Profile From Pro‐Inflammatory to Pro‐Tolerant

open access: yesAllergy, EarlyView.
This study investigates the effect of IL‐33 and Hymenoptera venom on mast cell cytokine profiles under venom immunotherapy (VIT)‐like conditions. Our in vitro model of VIT‐like mast cell stimulation demonstrates a modulatory effect of IL‐33 on the secreted mast cell cytokine profile.
Andrea R. Teufelberger   +3 more
wiley   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

open access: yesAndrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos   +4 more
wiley   +1 more source

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