Results 51 to 60 of about 23,863 (307)

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Machine Learning for Green Solvents: Assessment, Selection and Substitution

Advanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta, Janhavi Nistane, Abhishek Sose, Harikrishna Sahu, Rampi Ramprasad   +4 more
wiley   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

Advanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze, Maëlle Hardel, Marc Landry, Erwan Bezard, Jérôme Baufreton, Gilberto Fisone, François Georges   +15 more
wiley   +1 more source

Parallel FP-Growth Algorithm Based on Load Balance [PDF]

Jisuanji gongcheng, 2019
Aiming at the problem that the lookup operation of FP-Growth algorithm has a high time complexity,this paper proposes a new algorithm named LBPFP.The algorithm is based on PFP algorithm,which is added a hash table to the head table to achieve fast access
GAO Quan,WAN Xiaodong
doaj   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

A Distance-Encoded Bloom Filter for Fast NDN Name Lookup

Applied Sciences
Named data networking (NDN) is a content-centric network architecture that requires efficient name lookup to forward packets based on hierarchical content names.
Junghwan Kim, Myeong-Cheol Ko
doaj   +1 more source

Accurate querying of frequent subgraphs in power grid graph data

Global Energy Interconnection, 2019
With the development of information technology, the amount of power grid topology data has gradually increased. Therefore, accurate querying of this data has become particularly important. Several researchers have chosen different indexing methods in the
Aihua Zhou, Lipeng Zhu, Xinxin Wu, Hongbin Qiu   +3 more
doaj   +1 more source

A Novel Improvement With an Effective Expansion to Enhance the MD5 Hash Function for Verification of a Secure E-Document

IEEE Access, 2020
MD5 is a one-way cryptographic function used in various fields for maintaining data integrity. The application of a Hash function can provide much protection and privacy and subsequently reduce data usage.
Ammar Mohammed Ali, Alaa Kadhim Farhan
doaj   +1 more source

Securing Generative Artificial Intelligence with Parallel Magnetic Tunnel Junction True Randomness

Advanced Intelligent Systems, EarlyView.
True random numbers can protect generative artificial intelligence (GAI) models from attacks. A highly parallel, spin‐transfer torque magnetic tunnel junction‐based system is demonstrated that generates high‐quality, energy‐efficient random numbers.
Youwei Bao, Shuhan Yang, Hyunsoo Yang
wiley   +1 more source

Voxel‐SLAM: A Complete, Accurate, and Versatile Light Detection and Ranging‐Inertial Simultaneous Localization and Mapping System

Advanced Intelligent Systems, EarlyView.
: In this work, Voxel‐SLAM (simultaneous localization and mapping) is introduced: a complete, accurate, and versatile LiDAR (light detection and ranging) ‐inertial SLAM system consisting of five modules: initialization, odometry, local mapping (LM), loop closure (LC), and global mapping (GM), all employing the same map representation, an adaptive voxel
Zheng Liu, Haotian Li, Chongjian Yuan, Xiyuan Liu, Jiarong Lin, Rundong Li, Chunran Zheng, Bingyang Zhou, Wenyi Liu, Fu Zhang   +9 more
wiley   +1 more source