Results 101 to 110 of about 15,433 (137)

Mapping the Altered Landscape of TCR Repertoire in Autoimmune Diseases

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Autoimmune diseases arise from the breakdown of immune tolerance through complex interactions between genetic predisposition, environmental exposures, and adaptive immune responses. High‐throughput T‐cell receptor (TCR) repertoire sequencing has transformed our ability to characterize these responses, providing unprecedented insights into ...
Celine Albalaa, Martin Pezous, David Klatzmann, Encarnita Mariotti‐Ferrandiz   +3 more
wiley   +1 more source

Thyroid Ultrasonography in Differentiation between Graves’ Disease and Hashimoto’s Thyroiditis

, 2017
Objective: Graves’ disease and Hashimoto’s thyroiditis are the most common causes of hyper and hypothyroidism, respectively. Differentiation of these 2 diseases, if the patient is euthyroid, may sometimes be extremely difficult on the basis of ...
Tavanaa S., Pishdad P., Pishdad G. R., Jalli R., Pishdad R.   +4 more
core  

Activation of Anergic B Cells During Development of Autoimmunity

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT In healthy individuals, autoreactive B cells are normally silenced via central and peripheral tolerance mechanisms. In the periphery, when autoreactive B cells recognize self‐antigen via their B cell receptor (BCR) (signal 1) but do not receive T cell help (signal 2), they undergo the tolerance mechanism called anergy.
Mohammad Mansoor, Brandon K. Hilliard, Mia J. Smith   +2 more
wiley   +1 more source

Multi-ancestry genome-wide association analyses provide insights into the genetic basis of Hashimoto’s thyroiditis

Autoimmune hypothyroidism (Hashimoto’s thyroiditis) is common and has a strong genetic component. Here we performed multi-ancestry genome-wide association meta-analyses encompassing 48,694 Hashimoto’s thyroiditis cases, using a precise case definition ...
Ilze Konrade, Lynn B. Jorde, Lars G. Fritsche, Eirini Marouli, Marta R. Moksnes, Alexander Teumer, Rosalie B. T. M. Sterenborg, Yukinori Okada, Vesna Boraska Perica, Sundararajan Srinivasan, Bjørn Olav Åsvold, Raitis Peculis, Areti Papadopoulou, Marco Medici, XiCheng Song, Luka Brčić, Inga Steinbrenner, The Biobank Japan Project, Yong Li, Bhramar Mukherjee, Peter J. Sauer, Bin Wang, Jin Zhou, Maris Teder-Laving, Enrique Soto-Pedre, Joshua C. Denny, Melissa N. Bujnis, Anav Babbar, Graham Leese, Vita Rovite, Colin N. A. Palmer, Antoine Weihs, Andres Metspalu, Chenjie Zeng, Masahiro Kanai   +34 more
core   +1 more source

Ultrasonographic Assessment of Intima-Media Thickness (IMT), as a Surrogate of Future Atherosclerosis and Cardiac Diseases in Patients with Hashimoto’s Thyroiditis and Concomitant Celiac Disease: A Case-Control Study

Frontiers in Biomedical Technologies
Purpose: Intima-Media Thickness (IMT), which is frequently evaluated by B-mode ultrasound study, has been proved to be a reliable surrogate marker for atherosclerosis progression and a predictor of upcoming cardiovascular risks.
Maryam Alaei, Mohamad Ghazanfari Hashemi, Seyedeh Nooshin Miratashi Yazdi, Mohammad Ali Kaviani, Ali Asadifar, Sahand Adib Moradi, Khazar Adibmoradi Langaroudi, Helia Helali, Mina Mahboudi, Aynaz Gerami   +9 more
doaj   +1 more source

Thyroid antibody positivity in pregnancy is associated with altered reproductive hormone concentrations and placental growth in Lewis rats

The Journal of Physiology, Volume 604, Issue 17, Page 7464-7489, 1 September 2026.
Abstract figure legend Thyroid antibody positivity (TAb+) in pregnancy is associated with adverse pregnancy outcomes, but the mechanisms are unclear. This study developed a rodent model of TAb+ in pregnancy, induced prior to mating so that TAb+ exposure occurred throughout the pregnancy. TAb+ did not alter thyroid hormone concentrations and had minimal
Rebecca L. Brady, Nykola L. Kent, Anna G. Reid, Liana P. Paszkowski, Ashley S. Meakin, Dayna A. Zimmerman, Dinithi T. Mahaliyanage, Elliott S. Neal, Michael D. Wiese, Helle Bielefeldt‐Ohmann, Janna L. Morrison, James S. M. Cuffe   +11 more
wiley   +1 more source

Interactions of Lymphocytes, Thyrocytes and Fibroblasts in Hashimoto’s Thyroiditis: An Immunohistochemical and Ultrastructural Study

, 2011
<i>Background:</i> The mechanism of autoimmune reaction, a diffuse process consisting of a combination of epithelial cell destruction, lymphoid cellular infiltration, and fibrosis in Hashimoto’s thyroiditis, is not well known. The aim of this
Elzbieta Korobowicz, Iwona Ben-Skowronek, Roman Ciechanek, Leszek Szewczyk   +3 more
core   +1 more source

The Role of Childhood Traumas in Adult Hashimoto’s Thyroiditis [PDF]

Objective: Hashimoto’s thyroiditis (HT) is the most common autoimmune thyroid disease. There are studies suggesting that childhood traumas cause hypothalamic-pituitary-adrenal axis dysfunction in adulthood, which predisposes patients to autoimmune ...
Uğur Aydoğan, Hüseyin Demirci, Ebru Aydoğan   +2 more
core   +1 more source

Iodine Consumption and Hashimoto’s Thyroiditis: A Systematic Literature Review [PDF]

, 2020
Iodine deficiency is a global health problem that is affecting over 2 billion people worldwide and 50 million people are dealing with the health issues directly related to being iodine deficient.
Sandra Cracchiolo
core  

Forest plots of the association between Hashimoto’s thyroiditis and CLNM in CN0 patients.

, 2015
Forest plots of the association between Hashimoto’s thyroiditis and CLNM in CN0 patients.
Liang He (305820), Zhihong Wang (142713), Ting Zhang (102583), Wei Sun (93580), Xiabin Lan (802911), Siming Liu (256812), Wenwu Dong (802912), Hao Zhang (15339)   +7 more
core   +1 more source