Results 111 to 120 of about 1,084,168 (352)
The US dollar: Safe haven - Despite rising US current account deficit [PDF]
The empirical analysis in this paper supports the view that the status of the US dollar as a “safe haven” is closely related to the development of the US current account and the US net foreign debt.
Diekmann, Berend, Meurers, Martin
core
A historical review of the shad fisheries of North America [PDF]
A review of the relative productivity and value of the shad fisheries of North America as reflected in recorded commercial catches. A review of reasons for the decline that are biological and socioeconomic.
Kolb, Haven, Mansueti, Romeo
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
The Large Deviation Principle for Coarse-Grained Processes
The large deviation principle is proved for a class of $L^2$-valued processes that arise from the coarse-graining of a random field. Coarse-grained processes of this kind form the basis of the analysis of local mean-field models in statistical mechanics ...
Ellis, R. S., Haven, K., Turkington, B.
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Is Gold a Hedge or a Safe Haven? An Analysis of Stocks, Bonds and Gold [PDF]
This paper addresses two questions. First, we investigate whether gold is a hedge against stocks and/or bonds and second, we investigate whether gold is a safe haven for investors if either stocks or bonds fall. A safe haven is defined as a security that
Brian M. Lucey, Dirk G. Baur
core
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Unraveling the World-Wide Pollution Haven Effect [PDF]
This paper contributes to the debate on the existence of pollution haven effects by systematically measuring the pollution content of trade (measured by the polluction content of imports (PCI)) and decomposing it into three components: a ‘deep’ (i.e ...
Jaime de Melo +2 more
core

